Py J-Y
EFS Centre Atlantique, site d'Orléans, 14, avenue de l'Hôpital, 45072 Orléans cedex 2, France.
Transfus Clin Biol. 2010 Dec;17(5-6):334-40. doi: 10.1016/j.tracli.2010.09.166. Epub 2010 Nov 2.
Allogeneic red blood cells transfusion is always an immunological challenge and the choice of the blood products is crucial for the patient safety. But this choice may be hampered by the quality or the quantity of the available supply. In the end, the lack of transfusion may be more harmful than transfusion. The balance between patients' needs and blood centres supplying is always delicate. The conditions are not the same for all blood groups. Things are easier for the KEL1 phenotype, where the supply must ensure only 92.5% of KEL: -1 red blood cells instead of the 91% expected. More complicated is the situation for group O red blood cells with 47 versus 43%. But the major problem concerns RH: -1 red blood cells, for which the needs reach 20.1 versus 15%. These challenges require a lot of efforts from blood centres staffs to influence blood donors' recruitment and appointments. A justified and carefully selected blood products issuing may be of great help, especially for group O RH: -1 red blood cells. Therefore, hospital blood banks must have ad hoc procedures and a trained staff to put them into practice.
异体红细胞输血始终是一项免疫挑战，血液制品的选择对患者安全至关重要。但这种选择可能会受到可用血液供应的质量或数量的限制。最终，不输血可能比输血更有害。患者需求与血库供应之间的平衡始终很微妙。不同血型的情况不尽相同。对于KEL1血型表型来说情况较为简单，其供应只需确保92.5%的KEL：-1红细胞，而非预期的91%。对于O型红细胞，情况则更为复杂，所需比例为47%，而供应比例为43%。但主要问题在于RH：-1红细胞，其需求比例达到20.1%，而供应比例为15%。这些挑战需要血库工作人员付出大量努力来影响献血者的招募和预约。合理且精心挑选的血液制品发放可能会有很大帮助，尤其是对于O型RH：-1红细胞。因此，医院血库必须有专门的程序和经过培训的工作人员来付诸实践。
