Cerdas-Quesada César
Banco de Sangre Hospital Dr. Max Peralta J. Cartago, Costa Rica.
Transfus Apher Sci. 2010 Apr;42(2):105-8. doi: 10.1016/j.transci.2010.01.005. Epub 2010 Jan 25.
The development of alloantibodies and erythrocyte autoantibodies complicates transfusion therapy. The antibodies detection of potential clinical significance in 136 samples of Dr. Max Peralta J Hospital Blood Bank patients, Cartago, Costa Rica between 2004 and February, 2009 were evaluated. Transfusion of phenotypically matched blood for Rh and Kell systems proved to be effective in preventing alloimmunization because it been found in this study that there is good evidence that a high proportion of antibodies produced in response to transfusion are Rh and K specificity.
同种抗体和红细胞自身抗体的产生使输血治疗变得复杂。对2004年至2009年2月间哥斯达黎加卡塔戈市马克斯·佩拉尔塔·J博士医院血库136例患者样本中具有潜在临床意义的抗体检测进行了评估。事实证明,输注Rh和Kell系统表型匹配的血液可有效预防同种免疫,因为在本研究中发现,有充分证据表明,因输血产生的抗体中很大一部分具有Rh和K特异性。