correspondence and M.D., Dept. of Psychiatry and Behavioral Sciences, Emory University School of Medicine, 80 Jesse Hill Jr. Dr., P.O. Box 26238, Atlanta, GA 30303, USA.
Psychosomatics. 2010 Nov-Dec;51(6):529-31. doi: 10.1176/appi.psy.51.6.529.
Lithium toxicity has been shown to cause lasting neurological sequelae in certain cases.
The authors present a case of choreoathetosis in the aftermath of a presumed episode of lithium toxic reaction.
The patient was treated by aggressive rehydration; lithium and, ultimately, all psychotropic medication was withheld for a period.
The patient showed marked improvement in orientation and movement control; however, some of the choreoathetoid symptoms persisted.
Patients on combination therapy with lithium and other psychotropics need to be closely monitored for the development of choreoathetoid and other symptoms of overmedication.
锂中毒已被证明在某些情况下会导致持久的神经后遗症。
作者报告了一例锂中毒反应后出现舞蹈手足徐动症的病例。
对患者进行积极的补液治疗;锂和最终所有的精神药物都被停用了一段时间。
患者的定向和运动控制明显改善;然而,一些舞蹈手足徐动症的症状仍然存在。
接受锂与其他精神药物联合治疗的患者需要密切监测舞蹈手足徐动症和其他药物过量症状的发生。