• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

细针穿刺细胞学检查中的“细胞漩涡”及类似结构作为甲状腺乳头状癌的诊断线索:4例报告

"Cellular swirls" and similar structures on fine needle aspiration cytology as diagnostic clues to papillary thyroid carcinoma: a report of 4 cases.

作者信息

Kumar Surendra, Singh Neha, Siddaraju Neelaiah

机构信息

Department of Pathology, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry-605 006, India.

出版信息

Acta Cytol. 2010 Sep-Oct;54(5 Suppl):939-42.

PMID:21053573
Abstract

BACKGROUND

"Cellular swirls" are one of the recently recognized criteria for diagnosing papillary thyroid carcinoma (PTC). Following its initial description, no publications have appeared in the literature.

CASE

Thyroid aspirates from 4 adult patients, 3 with a clinical diagnosis of PTC and 1 diagnosed as nodular goiter were studied. Cytologically, all 4 cases showed classic features of PTC. In addition to the characteristic cytomorphology of PTC, all 4 cases showed cellular swirls, which are a newly recognized diagnostic criterion of PTC. Also seen were structures that partially resembled cellular swirls. These latter structures were found to be more prominent in the aspiration smears than the characteristic swirls and, therefore, we strongly think that even the partical swirls with contiguous cellular sheets exhibiting similar nuclear morphology are also useful in prompting a search for "complete swirls" that are thought to be specific for PTC.

CONCLUSION

Cellular swirls and similar structures seen on fine needle aspiration cytologic smears can serve as useful features in the diagnosis of PTC.

摘要

背景

“细胞漩涡”是最近被认可的诊断甲状腺乳头状癌(PTC)的标准之一。自其首次被描述以来,文献中尚未有相关出版物出现。

病例

对4例成年患者的甲状腺穿刺样本进行了研究,其中3例临床诊断为PTC,1例诊断为结节性甲状腺肿。细胞学检查显示,所有4例均具有PTC的典型特征。除了PTC的特征性细胞形态外,所有4例均显示出细胞漩涡,这是一种新认可的PTC诊断标准。还发现了部分类似于细胞漩涡的结构。这些后一种结构在穿刺涂片中比特征性漩涡更为突出,因此,我们强烈认为,即使是带有连续细胞片且呈现相似核形态的部分漩涡,对于促使寻找被认为是PTC特异性的“完整漩涡”也很有用。

结论

细针穿刺细胞学涂片上所见的细胞漩涡和类似结构可作为PTC诊断中的有用特征。

相似文献

1
"Cellular swirls" and similar structures on fine needle aspiration cytology as diagnostic clues to papillary thyroid carcinoma: a report of 4 cases.细针穿刺细胞学检查中的“细胞漩涡”及类似结构作为甲状腺乳头状癌的诊断线索:4例报告
Acta Cytol. 2010 Sep-Oct;54(5 Suppl):939-42.
2
[Thyroid papillary hyperplasia mistaken for papillary carcinoma in fine needle aspiration cytology and frozen section examination].[细针穿刺细胞学及冰冻切片检查中甲状腺乳头状增生被误诊为乳头状癌]
Ned Tijdschr Geneeskd. 2003 Mar 15;147(11):510-3.
3
Fine needle aspiration cytology of papillary carcinoma thyroid with Hashimoto's thyroiditis--report of two cases.甲状腺乳头状癌合并桥本甲状腺炎的细针穿刺细胞学检查——2例报告
Indian J Pathol Microbiol. 1997 Apr;40(2):165-8.
4
Diagnostic pitfalls in the evaluation of fine needle aspiration cytology of the thyroid: correlation with histopathology in 260 cases.甲状腺细针穿刺细胞学评估中的诊断陷阱:260例与组织病理学的相关性
Cytopathology. 2009 Apr;20(2):103-8. doi: 10.1111/j.1365-2303.2008.00594.x. Epub 2008 Aug 18.
5
Fine-needle aspiration biopsy of a papillary thyroid carcinoma involved by malignant plasma cell disease: a case report.
Diagn Cytopathol. 2009 Mar;37(3):217-9. doi: 10.1002/dc.21036.
6
Papillary thyroid carcinoma with atypical histiocytoid cells on fine-needle aspiration.细针穿刺显示具有非典型组织细胞样细胞的甲状腺乳头状癌。
Diagn Cytopathol. 2009 Apr;37(4):244-50. doi: 10.1002/dc.20990.
7
Papillary carcinoma of thyroid presenting with skin ulceration.甲状腺乳头状癌伴皮肤溃疡表现。
Cytopathology. 2007 Aug;18(4):269-71. doi: 10.1111/j.1365-2303.2006.00361.x.
8
Adenoid cystic variant of papillary thyroid carcinoma: a case report with fine-needle aspiration cytology.
Diagn Cytopathol. 2008 Jan;36(1):64-6. doi: 10.1002/dc.20716.
9
Predictors of malignancy in thyroid fine-needle aspirates "cyst fluid only" cases: can potential clues of malignancy be identified?
Cancer. 2009 Oct 25;117(5):305-10. doi: 10.1002/cncy.20041.
10
Cytologic features of mixed papillary carcinoma and chronic lymphocytic leukemia/small lymphocytic lymphoma of the thyroid gland.甲状腺混合性乳头状癌与慢性淋巴细胞白血病/小淋巴细胞淋巴瘤的细胞学特征。
Diagn Cytopathol. 2008 Nov;36(11):813-7. doi: 10.1002/dc.20894.

引用本文的文献

1
Value of Combined Cytomorphological Parameters in Improving Diagnostic Accuracy of Papillary Thyroid Carcinoma on Cytology - The Five Dependable Features.联合细胞形态学参数在提高甲状腺乳头状癌细胞学诊断准确性中的价值——五个可靠特征
Indian J Endocrinol Metab. 2021 Sep-Oct;25(5):402-409. doi: 10.4103/ijem.ijem_389_21. Epub 2022 Jan 12.
2
Deep Learning Fast Screening Approach on Cytological Whole Slides for Thyroid Cancer Diagnosis.用于甲状腺癌诊断的细胞学全切片深度学习快速筛查方法
Cancers (Basel). 2021 Aug 2;13(15):3891. doi: 10.3390/cancers13153891.
3
Cytomorphologic Diversity of Papillary Thyroid Carcinoma.
甲状腺乳头状癌的细胞形态学多样性
J Cytol. 2017 Oct-Dec;34(4):183-187. doi: 10.4103/JOC.JOC_164_16.
4
Intranuclear cytoplasmic inclusions in cytologically suspicious or malignant thyroid nodules: identification and correlation with echogenicity and size of the nodules.细胞学检查可疑或恶性甲状腺结节中的核内胞质包涵体:鉴定及其与结节回声性和大小的相关性
Endocrine. 2014 May;46(1):114-22. doi: 10.1007/s12020-013-0044-6. Epub 2013 Sep 25.