Wu Hong-yan, Yin Jin-fu
Department of Ophthalmology, People's Hospital of Dongyang, Dongyang, Zhejiang, China.
Zhonghua Yan Ke Za Zhi. 2010 Jun;46(6):494-8.
To investigate the medication adherence and modulation factors of medication adherence in long-term treated glaucoma patients.
It was a cross-sectional study. One hundred glaucoma patients who have been followed-up for more than 6 month in the Second Hospital affiliated to Medical College of Zhejiang University were investigated with questionnaires and interview. The data was analyzed by binary logistic regression and χ(2) test.
In the 100 glaucoma patients being investigated, the medication compliance of patients is 61(61.0%), the medication non-compliance of patients is 39 (39.0%). Age, gender, habitat, glaucoma types, surgical history, ingesting patient before writing out a prescription and informing them the methods for application of eyedrops were not significantly co-related with medication adherence (χ(2) = 0.718, 0.537, 0.338, 3.797, 0.338, 0.297, 0.157; P > 0.05). Intraocular pressure before treatment, types of eyedrops, instillation of eye-drops to the eyelids, request for help during application of eyedrops, rechecking regularly and confidence in glaucoma treatment were found significantly related to medication adherence (P = 0.013, 0.005, 0.005, 0.012, 0.011, 0.004). However, drug side effect, forgetting application of eyedrops and inconvenience to see a doctor was considered the most important factors by patients in the interview.
Glaucoma physicians should discuss with patients about the methods for the application of glaucoma medication. This can improve the medication adherence of glaucoma patients and promote the therapeutic effect.
探讨长期治疗的青光眼患者的用药依从性及影响用药依从性的因素。
这是一项横断面研究。对在浙江大学医学院附属第二医院随访6个月以上的100例青光眼患者进行问卷调查和访谈。采用二元logistic回归和χ²检验进行数据分析。
在被调查的100例青光眼患者中，用药依从性好的患者有61例（61.0%），用药依从性差的患者有39例（39.0%）。年龄、性别、居住地、青光眼类型、手术史、开处方前告知患者及告知眼药水使用方法与用药依从性无显著相关性（χ² = 0.718、0.537、0.338、3.797、0.338、0.297、0.157；P > 0.05）。治疗前眼压、眼药水类型、眼药水滴入眼睑的方式、滴眼药水时寻求帮助、定期复查以及对青光眼治疗的信心与用药依从性显著相关（P = 0.013、0.005、0.005、0.012、0.011、0.004）。然而，在访谈中患者认为药物副作用、忘记滴眼药水和看病不便是最重要的因素。
青光眼医生应与患者讨论青光眼药物的使用方法。这可以提高青光眼患者的用药依从性并促进治疗效果。
