Cecil G. Sheps Center for Health Services Research, Division of Pharmaceutical Outcomes and Policy, Eshelman School of Pharmacy, University of North Carolina, CB # 7590, Chapel Hill, NC 27599-7590, USA.
Br J Ophthalmol. 2012 Feb;96(2):258-62. doi: 10.1136/bjo.2010.199851. Epub 2011 May 24.
The aims of this study were: (1) to examine whether the original glaucoma medication adherence and eye drop technique self-efficacy scales could be shortened for easier use in practice settings; and (2) to validate these scales against objective medication adherence measures.
Prospective study conducted at a single private practice site. We measured subjects' adherence to glaucoma medications through Medication Event Monitoring System (MEMS) devices and assessed eye drop instillation technique by video-recording. Principal components factor analysis and logistic and linear regression were used to analyse the data.
Our results yielded a 10-item Glaucoma Medication Adherence Self-Efficacy Scale that was strongly associated with subject adherence measured using MEMS (β coefficient 8.52, 95% CI 1.94 to 15.1). In addition, the six-item Eye Drop Technique Self-Efficacy Scale was strongly associated with video-recorded subject eye drop installation technique (OR 10.47, 95% CI 1.78 to 61.63).
Eye care providers and researchers could use these shorter scales to identify subjects with either poor glaucoma medication adherence and/or eye drop instillation technique. This could help to identify those who may benefit most from education and training on both adherence and eye drop instillation.
本研究的目的是：(1) 检验原始的青光眼药物依从性和滴眼技术自我效能量表是否可以缩短，以便在实践环境中更方便地使用；(2) 通过客观的药物依从性测量来验证这些量表。
在一个单一的私人诊所进行前瞻性研究。我们通过药物事件监测系统（MEMS）设备测量受试者对青光眼药物的依从性，并通过视频记录评估滴眼技术。采用主成分因子分析和逻辑与线性回归对数据进行分析。
我们的研究结果得出了一个 10 项的青光眼药物依从性自我效能量表，该量表与使用 MEMS 测量的受试者依从性高度相关（β系数为 8.52，95%置信区间为 1.94 至 15.1）。此外，六项目的滴眼技术自我效能量表与视频记录的受试者滴眼安装技术高度相关（OR 10.47，95%置信区间为 1.78 至 61.63）。
眼保健提供者和研究人员可以使用这些较短的量表来识别药物依从性和/或滴眼技术较差的受试者。这有助于确定那些在药物依从性和滴眼技术方面最需要教育和培训的患者。
