Department of Pathology, College of Physicians and Surgeons, Columbia University, 630 West 168th Street-PH 15 West, Room 1574, New York, NY 10032, USA.
Clin Liver Dis. 2010 Nov;14(4):747-62. doi: 10.1016/j.cld.2010.07.007.
Recent publications on hepatology and hepatic pathology provide a wealth of new information on wideranging topics. Morphologic aspects of liver disease associated with hepatitis B and C viruses, autoimmune hepatitis, and HIV infection were addressed, as was the prevalent problem of nonalcoholic fatty liver disease. Advances in diagnosis and pathogenesis of primary biliary cirrhosis, primary sclerosing cholangitis, and the increasingly complex spectrum of IgG4 hepatobiliary diseases were also reported. The histologic and immunohistochemical features of the rare "calcifying nested stromal-epithelial tumor" of the liver were described in a 9-case series. For benign and malignant liver tumors, immunohistochemistry plays a major diagnostic role, and several recent studies demonstrate the value of immunostains in distinguishing between liver-cell adenoma and focal nodular hyperplasia.
最近发表的有关肝脏病学和肝脏病理学的文献提供了广泛主题的大量新信息。文中涉及与乙型肝炎和丙型肝炎病毒、自身免疫性肝炎和 HIV 感染相关的肝脏疾病的形态学方面，以及非酒精性脂肪性肝病这一普遍问题。原发性胆汁性胆管炎、原发性硬化性胆管炎和越来越复杂的 IgG4 肝胆疾病谱的诊断和发病机制方面的进展也有报道。9 例罕见的“巢状间质-上皮性钙化肿瘤”的肝脏组织学和免疫组化特征在一篇文章中进行了描述。对于良性和恶性肝肿瘤，免疫组化起着主要的诊断作用，几项最近的研究表明免疫组化在鉴别肝细胞腺瘤和局灶性结节性增生方面具有价值。
