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乐观和悲观对抑郁症诊断后工作残疾的预测作用:一项前瞻性队列研究的发病和恢复情况。

Optimism and pessimism as predictors of work disability with a diagnosis of depression: a prospective cohort study of onset and recovery.

机构信息

Department of Psychiatry, University of Turku, 20500 Turku, Finland.

出版信息

J Affect Disord. 2011 Apr;130(1-2):294-9. doi: 10.1016/j.jad.2010.10.003. Epub 2010 Nov 5.

DOI:10.1016/j.jad.2010.10.003
PMID:21055822
Abstract

BACKGROUND

Personality characteristics are assumed to affect to the vulnerability to depression and its outcomes. The aim of this study was to examine optimism and pessimism as predictors of depression-related work disability and subsequent return to work.

METHODS

We conducted a prospective cohort study of 38,214 public sector employees with no record of diagnosed depression. Optimism and pessimism were measured using the Revised Life Orientation Test (LOT-R). Records of long-term (>90 days) work disability with a diagnosis of depression and subsequent return to work until the end of 2005 were obtained from the national health registers.

RESULTS

During the mean follow-up of 4.0 (SD=2.3) years, 287 employees encountered work disability with a diagnosis of depression. Of them, 164 (57%) returned to work during the follow-up. One unit increase in the optimism mean score (range 1-4) was associated with a 25% lower risk of work disability due to depression and a 37% higher probability of returning to work after a work disability period when adjusted for age and sex. In the fully-adjusted model hazard ratios per one unit increase in optimism were 0.79 (95% CI 0.66-0.96) for work disability and 1.30 (95% CI 1.01-1.66) for return to work. The pessimism mean score (range 1-4) was only associated with a lower probability of returning to work (fully-adjusted HR per one unit increase 0.66, 95% Cl 0.49-0.88).

CONCLUSION

The level of optimism was a stronger predictor of work disability with a diagnosis of depression than the level of pessimism, while both optimism and pessimism predicted returning to work.

摘要

背景

个性特征被认为会影响到对抑郁症的易感性及其结果。本研究的目的是检验乐观和悲观作为抑郁相关工作残疾及其随后恢复工作的预测因素。

方法

我们对 38214 名无诊断性抑郁症记录的公共部门员工进行了前瞻性队列研究。使用修订后的生活取向测试(LOT-R)测量乐观和悲观。从国家健康登记处获得了有诊断性抑郁症的长期(>90 天)工作残疾记录和随后的工作恢复情况,直到 2005 年底。

结果

在平均 4.0(SD=2.3)年的随访期间,有 287 名员工因抑郁症而出现工作残疾。其中,164 人(57%)在随访期间恢复了工作。乐观平均得分(范围 1-4)每增加一个单位,与因抑郁导致工作残疾的风险降低 25%,以及在残疾期间后恢复工作的可能性增加 37%相关,调整年龄和性别后。在完全调整的模型中,乐观评分每增加一个单位,工作残疾的风险比为 0.79(95%CI 0.66-0.96),恢复工作的风险比为 1.30(95%CI 1.01-1.66)。乐观平均得分(范围 1-4)仅与恢复工作的可能性较低相关(完全调整的 HR 每增加一个单位为 0.66,95%Cl 0.49-0.88)。

结论

乐观程度是预测抑郁相关工作残疾的更强预测因素,而悲观程度则是预测恢复工作的因素。

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