Castillo M, Davis P C, Takei Y, Hoffman J C
Department of Radiology, Emory University Hospital, Atlanta, GA 30322.
AJNR Am J Neuroradiol. 1990 Jan-Feb;11(1):109-14.
Eighteen cases of pathologically proved intracranial gangliogliomas were reviewed to determine their MR, CT, and clinical characteristics. Seventeen patients were evaluated with contrast-enhanced CT and 14 were studied by MR imaging. Eight tumors were predominantly cystic; half of these demonstrated some contrast enhancement, and five contained calcifications. These cystic gangliogliomas were located, in order of decreasing frequency, in the cerebellum, temporal, frontal, and parietal lobes. Ten tumors were solid; eight of these showed contrast enhancement, and only one contained calcifications. Small cysts were present in one solid mass. Solid gangliogliomas occurred preferentially in the temporal lobes. On MR, the findings were nonspecific and reflected the CT findings. In one patient who received gadolinium-DTPA the lesion did not enhance. Clinically, all patients presented with nonfocal long-standing symptoms and all but three were alive an average of 18 months after the initial diagnosis. Pathologists are recognizing ganglioglioma with increasing frequency, and although its radiographic characteristics vary, it should be included in the differential diagnosis when the above-described findings are encountered.
回顾了18例经病理证实的颅内神经节胶质瘤病例，以确定其磁共振成像（MR）、计算机断层扫描（CT）及临床特征。17例患者接受了增强CT检查，14例进行了MR成像研究。8个肿瘤以囊性为主；其中半数有一定程度的强化，5个有钙化。这些囊性神经节胶质瘤按出现频率递减依次位于小脑、颞叶、额叶和顶叶。10个肿瘤为实性；其中8个有强化，仅1个有钙化。1个实性肿块内有小囊肿。实性神经节胶质瘤好发于颞叶。在MR上，表现无特异性，与CT表现相符。1例接受钆喷替酸葡甲胺（gadolinium-DTPA）检查的患者，病变无强化。临床上，所有患者均表现为非局灶性的长期症状，除3例患者外，其余患者在初次诊断后平均存活18个月。病理学家对神经节胶质瘤的认识日益增多，尽管其影像学特征各异，但当遇到上述表现时，鉴别诊断中应考虑到该病。
