Castillo M, Malko J A, Hoffman J C
Department of Radiology, Emory University School of Medicine, Emory University Hospital, Atlanta, GA 30322.
AJNR Am J Neuroradiol. 1990 Jan-Feb;11(1):23-6.
Two phantoms were constructed and imaged for the purpose of reproducing and understanding the relatively increased signal intensity of intervertebral disks on T1-weighted MR images in three patients with diffuse vertebral metastases. The first phantom simulated a normal spine and showed that the disks and vertebral bodies were of similar intensity. The second phantom simulated an abnormal spine and showed that the disks were brighter than the vertebrae. Prolonged relaxation times from the vertebral bodies as well as manipulation of the window width and level are the factors responsible for the presence of bright disks on T1-weighted images. Variations in the window width and level can accentuate the apparent increase in signal intensity from the disks but not reverse it. Although the presence of bright disks may be subtle, recognition of this sign should raise the possibility of diffuse replacement of normal fatty bone marrow in the vertebrae.
构建了两个模型并对其进行成像，目的是再现和理解三名弥漫性椎体转移患者在T1加权磁共振图像上椎间盘相对增强的信号强度。第一个模型模拟正常脊柱，显示椎间盘和椎体强度相似。第二个模型模拟异常脊柱，显示椎间盘比椎体更亮。椎体的弛豫时间延长以及窗宽和窗位的调整是导致T1加权图像上出现亮椎间盘的因素。窗宽和窗位的变化可增强椎间盘信号强度的明显增加，但不能使其逆转。尽管亮椎间盘的表现可能不明显，但识别该征象应提高椎体中正常脂肪骨髓被弥漫性替代的可能性。
