癌症重症患者的低白蛋白血症：发病率和死亡率
Hypoalbuminemia in critically ill patients with cancer: incidence and mortality.
作者信息
Ñamendys-Silva Silvio A, González-Herrera María O, Texcocano-Becerra Julia, Herrera-Gómez Angel
机构信息
Department of Critical Care Medicine, Instituto Nacional de Cancerología, Mexico City, Mexico.
出版信息
Am J Hosp Palliat Care. 2011 Jun;28(4):253-7. doi: 10.1177/1049909110384841. Epub 2010 Nov 7.
PURPOSE
The aim of this study was to investigate the incidence of hypoalbuminemia in critically ill patients with cancer and to describe the relationship of serum albumin levels to mortality.
DESIGN
An observational cohort study. There were no interventions.
RESULTS
During the study period, 200 patients were eligible for inclusion. A total of 164 (82%) patients had a serum albumin concentration below 35 g/L, of which 91 (55.5%) patients had levels of albumin ≤20 g/L. The mean serum albumin was 18.17 g/L. The crude mortality rate was 22.5%. The highest mortality rate (73%) was seen in the group of patients whose serum albumin levels were <20 g/L.
CONCLUSION
The incidence of hypoalbuminemia in critically ill patients with cancer admitted to ICU was high.
目的
本研究旨在调查危重症癌症患者低白蛋白血症的发生率，并描述血清白蛋白水平与死亡率的关系。
设计
一项观察性队列研究。未进行干预。
结果
在研究期间，200例患者符合纳入标准。共有164例（82%）患者血清白蛋白浓度低于35 g/L，其中91例（55.5%）患者白蛋白水平≤20 g/L。血清白蛋白平均水平为18.17 g/L。粗死亡率为22.5%。血清白蛋白水平<20 g/L的患者组死亡率最高（73%）。
结论
入住重症监护病房的危重症癌症患者低白蛋白血症的发生率较高。
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