Université catholique de Louvain, Cliniques universitaires de Mont-Godinne, 5530 Yvoir, Belgium.
Psychiatr Danub. 2010 Nov;22 Suppl 1:S132-4.
There is now some evidence that depressed mood is associated with activation of the immune system. First, we evaluated, within a cross-sectional design, NKCA (in vitro) in 49 subjects meeting inclusion criteria either for a major depressive episode, for dysthymia, or for "double depression". We found that recent and long depressive episodes (dysthymia) are associated with a lower immunodepression. Second, we compared two subset of subjects: 14 patients meeting criteria of major depression to 14 healthy controls. The data show a significant improvement in major depression when compared to controls througout a treatment combining supportive psychotherapy and 8 mg Reboxetine™.
现在有一些证据表明，抑郁情绪与免疫系统的激活有关。首先，我们在一个横断面设计中评估了 49 名符合主要抑郁发作、心境恶劣或“双重抑郁”纳入标准的受试者的 NKCA（体外）。我们发现，近期和长期的抑郁发作（心境恶劣）与较低的免疫抑制有关。其次，我们比较了两组受试者：14 名符合重度抑郁症标准的患者和 14 名健康对照者。数据显示，在一项结合支持性心理治疗和 8 毫克瑞波西汀的治疗中，与对照组相比，重度抑郁症患者有显著改善。
