Department of Chemistry, University of Missouri-Columbia, Columbia, Missouri 65211, USA.
Chem Commun (Camb). 2010 Dec 21;46(47):8886-903. doi: 10.1039/c0cc03620j. Epub 2010 Nov 8.
The (4+3)-cycloaddition of allylic cations to dienes is a powerful method for the direct synthesis of seven-membered rings. Recent developments in this area have included new methods for the generation of allylic cations, diastereoselective and catalytic, enantioselective reactions, an increased understanding of the diverse mechanistic possibilities of the reaction and applications to the total synthesis of natural products and their analogues.
烯丙基阳离子与二烯的[4+3]-环加成反应是一种直接合成七元环的有效方法。该领域的最新进展包括：新型烯丙基阳离子生成方法、非对映选择性和催化、对映选择性反应、对反应多种可能机理的深入理解以及在天然产物及其类似物的全合成中的应用。
