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单孔与标准腹腔镜胆囊切除术的病例对照研究。

A case-control study of single-incision versus standard laparoscopic cholecystectomy.

机构信息

Hepato-Pancreato-Biliary Division, Department of Surgery, National University Hospital Singapore, 5 Lower Kent Ridge Road, Singapore, 119074, Singapore.

出版信息

World J Surg. 2011 Feb;35(2):289-93. doi: 10.1007/s00268-010-0842-4.

Abstract

BACKGROUND

Single-incision laparoscopic cholecystectomy (SILC) has been increasingly performed recently. Although it seems plausible that SILC will be associated with less pain compared to standard 4-port laparoscopic cholecystectomy (LC), there is currently no conclusive comparative study on the postoperative pain issues of SILC against LC.

METHODS

In this retrospective, case-control study, 30 patients who had SILC over a 6-month period were compared with a matched (sex, age group, race) group of 30 patients who underwent LC. Verbal pain score (VPS) on postoperative days (POD) 1, 2, 3, and 5; pain sites; analgesic requirement; and number of days (NoD) required to return to normal activities were compared.

RESULTS

There were 4 (13%) acute cholecystitis cases in each group. Average VPS on POD 1, 2, 3, and 5 of SILC and (LC) cholecystectomy patients were 4.53 (5.14) (P=0.09), 3.43 (3.83) (P=0.36), 2.07 (2.52) (P=0.25), and 1.13 (1.24) (P=0.69), respectively. In the SILC group, 26 patients (87%) had umbilical pain, whereas in the LC group, 25 patients (83%) had similar symptoms. Epigastric pain was experienced by 5 patients in the two groups, and RHC pain was experienced by 1 patient in the SILC group (3%) and 2 patients in the LC group (7%). The SILC and the LC patients required 4.00 and 4.90 days (P=0.09) of paracetamol, respectively, to control pain. The NoD required before return to normal activity in the SILC and LC groups was 5.97 days and 7.79 days (P=0.008), respectively.

CONCLUSIONS

There was no statistically significant difference in postoperative pain, pain site and analgesia requirement; however, patients who underwent SILC returned to their normal activity 1.8 days earlier than the LC patients. Larger RCTs are needed to compare postoperative outcomes between SILC and LC.

摘要

背景

单切口腹腔镜胆囊切除术(SILC)最近越来越多地进行。尽管 SILC 似乎与标准的 4 孔腹腔镜胆囊切除术(LC)相比疼痛较轻,但目前尚无关于 SILC 与 LC 术后疼痛问题的明确对比研究。

方法

在这项回顾性病例对照研究中,比较了 6 个月内接受 SILC 的 30 例患者与接受 LC 的 30 例匹配(性别、年龄组、种族)患者。比较术后第 1、2、3、5 天的语言疼痛评分(VPS);疼痛部位;镇痛需求;以及恢复正常活动所需的天数(NoD)。

结果

每组各有 4 例(13%)急性胆囊炎。SILC 和(LC)胆囊切除术患者术后第 1、2、3、5 天的平均 VPS 分别为 4.53(5.14)(P=0.09)、3.43(3.83)(P=0.36)、2.07(2.52)(P=0.25)和 1.13(1.24)(P=0.69)。在 SILC 组中,26 例(87%)患者有脐部疼痛,而在 LC 组中,25 例(83%)患者有类似症状。两组各有 5 例患者出现上腹痛,SILC 组 1 例(3%)和 LC 组 2 例(7%)患者出现 RHC 疼痛。SILC 和 LC 患者分别需要 4.00 和 4.90 天(P=0.09)扑热息痛来控制疼痛。SILC 和 LC 组恢复正常活动前的 NoD 分别为 5.97 天和 7.79 天(P=0.008)。

结论

术后疼痛、疼痛部位和镇痛需求无统计学差异;然而,接受 SILC 的患者比接受 LC 的患者早 1.8 天恢复正常活动。需要更大规模的 RCT 来比较 SILC 和 LC 之间的术后结果。

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