Cetin Meral, Yildiz Caglar, Yenicesu Ayse G I, Cetin Ali
Department of Obstetrics and Gynecology, Cumhuriyet University School of Medicine, Sivas, Turkey.
J Obstet Gynaecol Res. 2010 Oct;36(5):1112-5. doi: 10.1111/j.1447-0756.2010.01256.x.
Cervico-isthmic pregnancy is a rare form of ectopic pregnancy and is defined as the implantation of a fertilized ovum in the cervico-isthmic portion. The cause is unknown; local pathology related to previous cervical or uterine surgery may play a role, given an apparent association with a prior history of curettage or cesarean delivery. Transvaginal ultrasonography and β-human chorionic gonadotrophin assays are useful for diagnosis. Here we report a case of spontaneous twin cervico-isthmic pregnancy in a grand multiparous patient who was diagnosed early in the first trimester with transvaginal ultrasonography. The pregnancy was terminated successfully with methotrexate. Methotrexate seems to be most successful at early gestational ages.
宫颈峡部妊娠是一种罕见的异位妊娠形式，定义为受精卵在宫颈峡部着床。病因不明；鉴于其与刮宫或剖宫产史明显相关，既往宫颈或子宫手术相关的局部病理可能起作用。经阴道超声检查和β-人绒毛膜促性腺激素测定有助于诊断。在此，我们报告一例多产患者自发性双宫颈峡部妊娠病例，该患者在孕早期通过经阴道超声检查得以早期诊断。妊娠通过甲氨蝶呤成功终止。甲氨蝶呤在孕早期似乎最为有效。
