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甲氨蝶呤给药后行双极切除术成功治疗宫颈-峡部妊娠:病例报告及文献复习。

Cervico-isthmic pregnancy successfully treated with bipolar resection following methotrexate administration: case report and literature review.

机构信息

Department of Obstetrics and Gynaecology and Pathophisiology of Reproduction, University of Naples 'Federico II', Italy.

出版信息

Reprod Biomed Online. 2013 Jan;26(1):99-103. doi: 10.1016/j.rbmo.2012.10.005. Epub 2012 Oct 12.

Abstract

Cervico-isthmic pregnancy is a rare form of ectopic pregnancy associated with a high morbidity and mortality rate. Recent advances in high-resolution ultrasound have made the diagnosis of early cervico-isthmic pregnancies easier. Early diagnosis allows a more conservative therapeutic approach that avoids hysterectomy and preserves fertility. Here is reported a case of viable cervico-isthmic pregnancy successfully treated with resectoscopy after failed systemic and local (hysteroscopic) methotrexate administration. The resectoscopic excision of the cervico-isthmic pregnancy was carried out with the technique of slicing, using a 27 bipolar resectoscope with a 4-mm loop. The procedure was successful with the complete removal of the ectopic pregnancy, while maintaining satisfactory haemostasis. A literature review shows that no consensus exists for the treatment of cervico-isthmic pregnancies. We report a case of viable cervico-isthmic pregnancy successfully treated with resectoscopy after failed systemic and local (hysteroscopical) methotrexate administration. The resectoscopic excision of cervico-isthmic pregnancy was carried out with the technique of slicing, using a 27 bipolar resectoscope with a 4-mm loop. The procedure was successful with the complete removal of the ectopic pregnancy, while maintaining satisfactory haemostasis.

摘要

宫颈-峡部妊娠是一种罕见的异位妊娠形式,其发病率和死亡率均较高。近年来,高分辨率超声技术的进步使得早期宫颈-峡部妊娠的诊断变得更加容易。早期诊断可以采取更保守的治疗方法,避免子宫切除术并保留生育能力。本文报告了一例成功接受宫腔镜下局部甲氨蝶呤治疗失败后行宫腔镜下切除术治疗的活胎宫颈-峡部妊娠。采用 27 双极电切镜和 4mm 环进行切片式切除宫颈-峡部妊娠。该手术成功地完全切除了异位妊娠,同时保持了满意的止血效果。文献复习显示,对于宫颈-峡部妊娠的治疗尚无共识。我们报告了一例成功接受宫腔镜下局部甲氨蝶呤治疗失败后行宫腔镜下切除术治疗的活胎宫颈-峡部妊娠。采用 27 双极电切镜和 4mm 环进行切片式切除宫颈-峡部妊娠。该手术成功地完全切除了异位妊娠,同时保持了满意的止血效果。

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