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[放射成像技术在慢性阻塞性支气管肺炎病理生理机制研究中的作用。第一部分。成像在慢性阻塞性肺疾病所致呼吸性病变研究中的作用]

[The role of radio-imaging techniques in the investigation of the pathophysiologic mechanisms in chronic obstructive bronchopneumonia. Part I. Role of imaging in the investigation of respiratory lesions caused by COPD].

作者信息

Ungurean Ioana, Tudorache Voicu, Mogoşeanu Maria, Marc Monica

机构信息

Disciplina de radiologie, Universitatea de Medicina şi Farmacie Victor Babeş, Timişoara.

出版信息

Pneumologia. 2010 Jul-Sep;59(3):144-51.

Abstract

Chronic obstructive pulmonary disease (COPD) is a common disease (4-6% of adults), with insidious onset and slow progression, which is why the disease remains under diagnosed especially in early stages. Most patients get medical attention in stage III, IV of disease, according to GOLD classification (Global Obstructive Lung Diseases). According to GOLD, priority in staging the disease severity is the evaluation of respiratory function, the FEV1. However radiographic evaluation of patients with risk (smokers or those working in polluted environment) may represent a first step in marking the changes in the lung and especially comorbidities. Since this disease is causing disability and a major socioeconomic problem, modern investigations, such as spiral computerised tomography (CT), multidetector computerised tomography (MDCT) and magnetic resonance (MRI) may be alternatives in diagnosis and early detection of disease.

摘要

慢性阻塞性肺疾病(COPD)是一种常见疾病(占成年人的4 - 6%),起病隐匿,进展缓慢,这就是该疾病尤其是在早期仍未得到充分诊断的原因。根据全球慢性阻塞性肺疾病倡议(GOLD)分类,大多数患者在疾病的III期、IV期才就医。根据GOLD,对疾病严重程度进行分期时,首要任务是评估呼吸功能,即第一秒用力呼气容积(FEV1)。然而,对有风险人群(吸烟者或在污染环境中工作的人)进行影像学评估可能是发现肺部变化尤其是合并症的第一步。由于这种疾病会导致残疾并带来重大的社会经济问题,现代检查手段,如螺旋计算机断层扫描(CT)、多排探测器计算机断层扫描(MDCT)和磁共振成像(MRI),可能是诊断和早期发现该疾病的替代方法。

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