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凝血因子浓缩物干热法可防止非甲非乙型肝炎传播的血清学证据。

Serological evidence that dry heating of clotting factor concentrates prevents transmission of non-A, non-B hepatitis.

作者信息

Skidmore S J, Pasi K J, Mawson S J, Williams M D, Hill F G

机构信息

Regional Virus Laboratory, East Birmingham Hospital, England.

出版信息

J Med Virol. 1990 Jan;30(1):50-2. doi: 10.1002/jmv.1890300111.

Abstract

A new test for antibodies specific for an agent causing non-A, non-B hepatitis (NANBH) was used to screen 45 children with coagulation disorders who received factor concentrates. It was found that the test results correlated with clinical evidence of NANBH and that heat treatment of concentrates (80 degrees C for 72 hours) appears to have prevented transmission of NANBH.

摘要

一种针对引起非甲非乙型肝炎(NANBH)病原体的特异性抗体新检测方法,被用于筛查45名接受凝血因子浓缩剂治疗的凝血功能障碍儿童。结果发现,检测结果与NANBH的临床证据相关,且浓缩剂经热处理(80摄氏度,72小时)似乎可预防NANBH的传播。

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