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两家医院诊所对癫痫患者进行酒精诱发癫痫发作的研究。

Seizure induction by alcohol in patients with epilepsy experience in two hospital clinics.

作者信息

Heckmatt J, Shaikh A A, Swash M, Scott D F

机构信息

Department of Neurology, Newham General Hospital, London.

出版信息

J R Soc Med. 1990 Jan;83(1):6-9. doi: 10.1177/014107689008300105.

Abstract

We surveyed 70 epileptic patients attending a general neurology clinic and 64 patients attending an epilepsy clinic to determine the incidence of alcohol-related seizures. Seven (10%) of the neurology clinic patients and 9 (15%) of the epilepsy clinic patients reported exacerbation of their seizures with alcohol. In the first group, two had been heavy drinkers when under-age, two had features of alcohol dependence, and three had experienced resolution of seizures following cessation of their drinking. In the second group, five drank 4 units/day or more, and one drank more heavily. The importance of alcohol in the causation of these patients' seizures had not previously been appreciated. The relationship of alcoholism to epilepsy has been recognized for many years, but the role of alcohol in the exacerbation of primary epilepsy, and in triggering seizures in epileptic patients is often not recognized. Control of alcohol ingestion is an important factor in the management of epilepsy.

摘要

我们对70名在普通神经科门诊就诊的癫痫患者和64名在癫痫门诊就诊的患者进行了调查,以确定与酒精相关的癫痫发作的发生率。神经科门诊患者中有7名(10%),癫痫门诊患者中有9名(15%)报告饮酒会使癫痫发作加剧。在第一组中,两人在未成年时曾是酗酒者,两人有酒精依赖的特征,三人在戒酒之后癫痫发作得到缓解。在第二组中,五人每天饮酒4单位及以上,一人饮酒量更大。此前人们并未认识到酒精在这些患者癫痫发作病因中的重要性。酒精中毒与癫痫的关系多年来已为人所知,但酒精在原发性癫痫发作加剧以及在癫痫患者中引发癫痫发作方面的作用往往未被认识到。控制酒精摄入是癫痫治疗中的一个重要因素。

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本文引用的文献

2
Occurrence of cerebral seizures provoked by alcohol abuse.酗酒引发的脑部癫痫发作情况。
Epilepsia. 1980 Oct;21(5):459-66. doi: 10.1111/j.1528-1157.1980.tb04296.x.
6
The role of abstinence in the genesis of alcoholic epilepsy.戒酒在酒精性癫痫发病中的作用。
Epilepsia. 1967 Mar;8(1):1-20. doi: 10.1111/j.1528-1157.1967.tb03815.x.
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Alcohol, seizures and epilepsy.酒精、癫痫发作与癫痫
J R Soc Med. 1987 Sep;80(9):542-3. doi: 10.1177/014107688708000903.
10
Alcohol consumption and withdrawal in new-onset seizures.
N Engl J Med. 1988 Sep 15;319(11):666-73. doi: 10.1056/NEJM198809153191102.

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