Nagao Yuichi, Shimajiri Shohei, Katsuki Takefumi, Nakayama Yoshifumi, Yamaguchi Koji
Department of Pathology and Cell Biology, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan.
Case Rep Gastroenterol. 2010 Sep 15;4(3):351-355. doi: 10.1159/000320682.
Heterotopic bone is rarely present in malignant tumors of the gastrointestinal tract. We herein report a case of rectal adenocarcinoma with heterotopic bone. A 46-year-old Japanese male presented to our hospital with abdominal distension and constipation. Colonoscopic examination showed an ulcerated polypoid tumor of the rectum which nearly obstructed the rectal lumen. Abdominal computed tomography showed a tumor of the rectum with calcified deposits. Low anterior resection with lateral lymph node dissection was performed under the tentative diagnosis of rectal cancer. Histological examination of the resected specimen showed mucinous carcinoma of the rectum with heterotopic bone. One of the metastatic lymph nodes dissected also showed heterotopic bone. In the present report, we describe this rare tumor and briefly review the pertinent literature regarding rectal cancer with heterotopic bone.
异位骨很少出现在胃肠道恶性肿瘤中。我们在此报告一例伴有异位骨的直肠腺癌病例。一名46岁的日本男性因腹胀和便秘前来我院就诊。结肠镜检查显示直肠有一个溃疡性息肉样肿瘤,几乎阻塞了直肠腔。腹部计算机断层扫描显示直肠有一个伴有钙化沉积物的肿瘤。在直肠癌的初步诊断下,进行了低位前切除术和侧方淋巴结清扫术。切除标本的组织学检查显示为伴有异位骨的直肠黏液癌。清扫出的一个转移淋巴结也显示有异位骨。在本报告中,我们描述了这种罕见肿瘤,并简要回顾了有关伴有异位骨的直肠癌的相关文献。