Morikawa Teppei, Goto Akiteru, Nishimatsu Hiroaki, Fukayama Masashi
Department of Pathology, Graduate School of Medicine, University of Tokyo, Tokyo, Japan.
Case Rep Oncol. 2010 Sep 14;3(3):334-338. doi: 10.1159/000320939.
We report an extremely rare case of small intestinal cancer metastasized to the urinary bladder, presenting a urologic symptom. A 41-year-old man first presented with nausea, vomiting and abdominal pain. Based on the clinical diagnosis of jejunal cancer, he underwent a partial resection of the jejunum with lymph node dissection. The pathological diagnosis was moderately differentiated adenocarcinoma of the jejunum, pT4N0. Seventeen months after surgery, he presented with a gross hematuria. Computed tomographic scan showed wall thickening of the posterior wall of the urinary bladder. No tumor was found in other organs or lymph nodes. Based on histological and immunohistochemical analysis, the diagnosis of urinary bladder metastasis from jejunal adenocarcinoma was made. This is the first report of urinary bladder metastasis from small intestinal cancer. Although very rare, the possibility of metastatic small intestinal cancer should be considered in differential diagnosis in patients with adenocarcinoma involving the urinary bladder.
我们报告了一例极为罕见的小肠癌转移至膀胱并出现泌尿系统症状的病例。一名41岁男性最初表现为恶心、呕吐和腹痛。基于空肠癌的临床诊断,他接受了空肠部分切除术及淋巴结清扫术。病理诊断为空肠中度分化腺癌,pT4N0。术后17个月,他出现肉眼血尿。计算机断层扫描显示膀胱后壁增厚。其他器官及淋巴结未发现肿瘤。基于组织学和免疫组化分析,诊断为空肠腺癌转移至膀胱。这是小肠癌转移至膀胱的首例报告。尽管非常罕见,但在膀胱腺癌患者的鉴别诊断中应考虑转移性小肠癌的可能性。