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登革病毒感染相关的急性横贯性脊髓炎

Acute transverse myelitis associated with dengue viral infection.

作者信息

Chanthamat Nouansompheng, Sathirapanya Pornchai

机构信息

Department of Internal Medicine, Prince of Songkla University, Hat yai, Songkhla, Thailand.

出版信息

J Spinal Cord Med. 2010;33(4):425-7. doi: 10.1080/10790268.2010.11689722.

Abstract

BACKGROUND

Acute transverse myelitis is a rare manifestation of dengue viral infection. Four cases have been previously reported in the literature.

OBJECTIVE

To report a case of a 61-year-old woman who developed acute transverse myelitis 6 days after the onset of a dengue viral infection.

FINDINGS

Magnetic resonance imaging of spinal cord showed hypersignal intensity on T2W at T9-T10. Laboratories studies revealed a high titer of hemagglutination inhibition of dengue virus. Treatment with intravenous pulse methylprednisolone and physiotherapy yielded a partial recovery, followed by complete resolution at 1 year postinfection.

CONCLUSION

Acute transverse myelitis is a rare manifestation of dengue infection that can occur in either the peri-infectious or postinfectious phases.

摘要

背景

急性横贯性脊髓炎是登革病毒感染的一种罕见表现。此前文献中已报道过4例。

目的

报告1例61岁女性,在登革病毒感染发病6天后发生急性横贯性脊髓炎。

结果

脊髓磁共振成像显示T9 - T10水平T2加权像上高信号强度。实验室检查显示登革病毒血凝抑制试验滴度高。静脉注射甲基强的松龙脉冲治疗及物理治疗后部分恢复,感染后1年完全恢复。

结论

急性横贯性脊髓炎是登革热感染的一种罕见表现,可发生在感染期或感染后期。

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Preferential gray matter involvement in dengue myelitis.登革热脊髓炎中灰质的优先受累情况。
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Isolation of dengue 2 virus from a patient with central nervous system involvement (transverse myelitis).
Rev Soc Bras Med Trop. 2002 Jul-Aug;35(4):401-4. doi: 10.1590/s0037-86822002000400018.
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Neurological manifestations of dengue infection.登革热感染的神经学表现。
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Dengue encephalitis: a true entity?登革热脑炎:一种真实存在的病症?
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