Departments of Pathology Neurosurgery Radiology, Chinese PLA General Hospital, Beijing, China.
Neuropathology. 2011 Aug;31(4):414-20. doi: 10.1111/j.1440-1789.2010.01160.x. Epub 2010 Nov 9.
Meningeal melanocytoma is an uncommon pigmented neoplasm that affects the CNS and develops in the cranial and spinal leptomeninges. Here we report on a case of malignant transformation of intracranial supratentorial meningeal melanocytoma which recurred after 3 years as malignant melanoma. This case demonstrates that the biological behavior of melanocytoma is uncertain and that these lesions may recur as malignant melanoma.
脑脊膜黑色素细胞瘤是一种少见的色素性肿瘤,影响中枢神经系统,发生于颅腔和脊髓的软脑膜。本文报告了 1 例颅内幕上脑膜黑色素细胞瘤恶性转化为恶性黑色素瘤,3 年后复发。该病例表明黑色素细胞瘤的生物学行为不确定,这些病变可能复发为恶性黑色素瘤。