Hamasaki Osamu, Nakahara Toshinori, Sakamoto Shigeyuki, Kutsuna Munenori, Sakoda Katsuaki
Department of Neurosurgery, Mazda Hospital, Hiroshima, Japan.
Neurol Med Chir (Tokyo). 2002 Nov;42(11):504-9. doi: 10.2176/nmc.42.504.
A 59-year-old man presented with a rare intracranial meningeal melanocytoma in the left cerebellopontine angle. The patient underwent partial surgical excision and radiosurgery for successful control of the tumor. Meningeal melanocytoma is an essentially benign melanotic tumor, derived from the melanocytes of the leptomeninges, and may occur anywhere in the cranial and spinal meninges. Preoperative differential diagnosis of intracranial meningeal melanocytoma from malignant melanoma is difficult based on magnetic resonance imaging. Ultrastructural findings are essential to establish the diagnosis. The prognosis of this tumor is not always favorable with occasional local recurrence. Total resection is the best treatment, but gamma knife radiosurgery is effective for the residual tumor following partial resection.
一名59岁男性患者,其左侧小脑桥脑角出现罕见的颅内脑膜黑素细胞瘤。患者接受了部分手术切除及放射外科治疗,肿瘤得到成功控制。脑膜黑素细胞瘤本质上是一种良性黑素瘤,起源于软脑膜的黑素细胞,可发生于颅和脊髓脑膜的任何部位。基于磁共振成像,术前将颅内脑膜黑素细胞瘤与恶性黑色素瘤进行鉴别诊断较为困难。超微结构检查结果对于确诊至关重要。该肿瘤的预后并非总是良好,偶尔会出现局部复发。全切除是最佳治疗方法,但伽玛刀放射外科对于部分切除后的残留肿瘤有效。