Deschamps D, Richard A, Citron B, Chaperon A, Binon J P, Ponsonnaille J
Service de cardiologie 6e étage, CHU Saint-Jacques, Clermont-Ferrand.
Arch Mal Coeur Vaiss. 1990 Jan;83(1):63-7.
The problem of pacing patients with carotid sinus hypersensitivity (CSH) is the choice and criteria of selection of the pacing mode. The authors studied 29 patients with CSH treated by VVI pacing over a period of 10 years. The average follow-up was 34 months (range 6 to 96 months). Three of the 27 patients (11%) who were asymptomatic at the outset continued to have symptoms. The nature of the CSH was well-defined in 25 patients; 19 of the 20 cases of cardio-inhibitory CSH and 4 of the 5 cases of mixed CSH were asymptomatic. These two poor clinical results were analysed: the patient with the cardio-inhibitory CSH (one recurrence in 84 months) had a drop of 40 mmHg in systolic blood pressure which fulfilled criteria of the cardio-inhibitory form of CSH (a drop of 30 to 50 mmHg). The second case was a complete therapeutic failure with 3 recurrent syncopal episodes. The patient had a mixed form of CSH (B.P. drop of 65 mmHg) associated with a "pace maker syndrome" (drop of 50 mmHg in systolic blood pressure at the onset of VVI pacing without any sino carotid massage). The authors conclude that the cases of CSH which, during their investigation, are best corrected by dual-chamber pacing or which are associated with a significant pacemaker effect or present retrograde ventriculo-atrial conduction, should receive dual-chamber pacemakers.
对于患有颈动脉窦过敏症(CSH)的患者进行起搏治疗的问题在于起搏模式的选择和选择标准。作者对29例接受VVI起搏治疗的CSH患者进行了为期10年的研究。平均随访时间为34个月(范围6至96个月)。最初无症状的27例患者中有3例(11%)仍有症状。25例患者的CSH性质明确;20例心脏抑制型CSH中的19例以及5例混合型CSH中的4例无症状。分析了这两个不佳的临床结果:心脏抑制型CSH患者(84个月内复发1次)收缩压下降40 mmHg,符合心脏抑制型CSH的标准(下降30至50 mmHg)。第二例是完全治疗失败,出现3次复发性晕厥发作。该患者为混合型CSH(血压下降65 mmHg),伴有“起搏器综合征”(VVI起搏开始时无任何窦颈动脉按摩,收缩压下降50 mmHg)。作者得出结论,对于那些在检查期间通过双腔起搏能得到最佳纠正、或与显著起搏器效应相关、或存在逆行室房传导的CSH病例,应植入双腔起搏器。