Blanc J J, Boschat J, Penther P
Arch Mal Coeur Vaiss. 1984 Mar;77(3):330-6.
The aim of this study was to assess the incidence and natural history of carotid sinus hypersensitivity (CSH) with respect to treatment and symptoms. Between May 1976 and December 1981, 714 patients underwent carotid sinus massage (CSM) during electrophysiological investigation (271 for syncope, 163 for dizziness); 79 had a pathological response (sinus arrest for over 3 s or two successive pauses of over 2 s each). Twenty five of these patients were excluded from the study group; 23 had the sick sinus syndrome or an associated AV block, and two were lost to follow-up. The remaining 54 patients were divided into two groups: Group I, comprising 33 patients who were given no treatment, and Group II, comprising 21 patients who were treated by permanent pacing. The patients in Group I were followed up for an average of 29 +/- 16 months and those in Group II for 25 +/- 22 months. Nine of the 18 patients in Group I, hospitalised for syncope, but none of the 5 patients admitted for dizziness alone, relapsed during follow-up. Only 1 patient without syncope or dizziness at the time of investigation reported having had a syncope during follow-up. The actuarial graph of absence of syncope fell regularly in Group I (58 p. 100 at 5 years), 4 patients in Group I were then given demand pacemakers and there was no further recurrence of syncope (follow-up: 34 +/- 15 months). Only 1 patient, admitted for dizziness, out of the 21 patients in Group II (13 syncopes, 8 cases of dizziness) continued to complain of the symptoms for which he had been paced.(ABSTRACT TRUNCATED AT 250 WORDS)
本研究旨在评估颈动脉窦过敏(CSH)在治疗和症状方面的发生率及自然病史。1976年5月至1981年12月期间,714例患者在电生理检查时接受了颈动脉窦按摩(CSM)(271例因晕厥,163例因头晕);79例有病理反应(窦性停搏超过3秒或连续两次停顿各超过2秒)。其中25例患者被排除在研究组之外;23例患有病态窦房结综合征或相关房室传导阻滞,2例失访。其余54例患者分为两组:第一组,33例未接受治疗的患者;第二组,21例接受永久性起搏治疗的患者。第一组患者平均随访29±16个月,第二组患者平均随访25±22个月。第一组因晕厥住院的18例患者中有9例在随访期间复发,但仅因头晕入院的5例患者均未复发。仅1例在检查时无晕厥或头晕的患者报告在随访期间发生过晕厥。第一组无晕厥的精算图呈规律性下降(5年时为58%),第一组中有4例患者随后接受了按需起搏器治疗,晕厥未再复发(随访:34±15个月)。第二组21例患者(13例晕厥,8例头晕)中,仅1例因头晕入院的患者继续诉说其起搏治疗的症状。(摘要截断于250字)