Yokomizo Yumiko, Fujikawa Atsushi, Tajiri Takehiro, Ota Junichi, Yumura Yasushi, Moriyama Masatoshi, Mouri Shinobu
The Department of Urology, Yokohama Municipal citizen's Hospital, Japan.
Hinyokika Kiyo. 2010 Oct;56(10):585-8.
An 81-year-old male with hormone refractory prostate cancer, received chemotherapy of Docetaxel, Estramustine and dexamethasone as an outpatient. After 4 courses of chemotherapy, he was admitted to our hospital in December 2007 because of general fatigue, appetite loss and erythema of the back of hands and face. He was diagnosed with pellagra. Nicotinic acid was administered and the symptoms disappeared. An 80-year-old male with hormone refractory prostate cancer, received chemotherapy of Docetaxel, Estramustine and dexamethasone without admission. After 8 courses of the chemotherapy, appetite loss appeared. In January 2008, medical examinations revealed nails peeling off, facial erythema and erosion of the back of his hands. He was diagnosed with pellagra. Nicotinic acid was administered and the symptoms disappeared. Pellagra, a nicotinic acid deficiency disease, is rarely observed clinically nowadays. However, it may occur in the patients, undergoing chemotherapy without admission.
一名81岁患有激素难治性前列腺癌的男性患者，在门诊接受了多西他赛、雌莫司汀和地塞米松化疗。4个疗程化疗后，于2007年12月因全身乏力、食欲减退以及手背和面部红斑入住我院。他被诊断为糙皮病。给予烟酸治疗后症状消失。一名80岁患有激素难治性前列腺癌的男性患者，未住院接受了多西他赛、雌莫司汀和地塞米松化疗。8个疗程化疗后出现食欲减退。2008年1月，医学检查发现指甲脱落、面部红斑和手背糜烂。他被诊断为糙皮病。给予烟酸治疗后症状消失。糙皮病是一种烟酸缺乏症，如今在临床上很少见。然而，它可能发生在未住院接受化疗的患者中。
