Balci Canan, Karabekir Hamit S, Yigit Muhammet
Department of Anesthesiology, Afyon Kocatepe University, Afyonkarahisar, Turkey.
Neurosciences (Riyadh). 2008 Apr;13(2):122-6.
To identify the entropy levels that would correspond to bispectral index (BIS) levels in general anesthesia (GA) induction in patients who will undergo elective lumbar disc surgery (LDS).
Thirty cases who underwent LDS under GA were included in our study after obtaining patient consent and approval of the Ethics Committee of Afyon Kocatepe University Medical School, Afyonkarahisar, Turkey, between January 01, 2004 to December 31, 2005. Bispectral index and entropy electrodes were applied at the same time to 30 cases in the study group. In order to assess the level of sedation during anesthesia and recovery, Observers Assessment of Alertness/Sedation` (OAA/S) scale was used. Bispectral index, state-entropy (SE), response-entropy (RE), and OAA/S values were recorded simultaneously.
Induction OAA/S scores were in correlation with BIS and entropy values (RE-SE) in 30 cases. A significant difference was found between BIS and entropy induction values (p=0.0398). Induction mean arterial pressure and heart rate values at 30, 60, 90, and 120 seconds were lower than the values of the control, which was statistically significant (p=0.0412).
During the induction of GA, we found entropy values to be more sensitive and they demonstrated a more rapid increase than BIS. Therefore, it would be safer to monitor entropy while using agents of induction that might cause severe hypotension. Induction agents that might cause severe hypotension could be more safely administered under entropy monitoring.
Notice of Duplicate Publication in: Neurosciences 2009; Vol. 14 (1): 106.
确定在接受择期腰椎间盘手术(LDS)的患者全身麻醉(GA)诱导过程中,与脑电双频指数(BIS)水平相对应的熵水平。
2004年1月1日至2005年12月31日期间,在获得患者同意并经土耳其阿菲永卡珀泰普大学医学院伦理委员会批准后,选取30例行GA下LDS手术的患者纳入本研究。研究组的30例患者同时应用BIS和熵电极。为评估麻醉及苏醒过程中的镇静水平,采用“观察者警觉/镇静评分”(OAA/S)量表。同时记录BIS、状态熵(SE)、反应熵(RE)及OAA/S值。
30例患者诱导期OAA/S评分与BIS及熵值(RE-SE)相关。BIS与熵诱导值之间存在显著差异(p=0.0398)。诱导期30、60、90及120秒时的平均动脉压和心率值低于对照组,差异有统计学意义(p=0.0412)。
在GA诱导过程中,我们发现熵值更敏感,且其升高速度比BIS更快。因此,在使用可能导致严重低血压的诱导药物时,监测熵会更安全。在熵监测下可更安全地给予可能导致严重低血压的诱导药物。
重复发表声明:发表于《神经科学》2009年;第14卷(1):106。