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尼泊尔博卡拉一家三级护理教学医院50例皮肤结核的临床流行病学研究。

A clinicoepidemiological study of 50 cases of cutaneous tuberculosis in a tertiary care teaching hospital in pokhara, Nepal.

作者信息

Dwari Binayak Chandra, Ghosh Arnab, Paudel Raju, Kishore P

机构信息

Department of Dermatology, Manipal Teaching Hospital & Manipal College of Medical Sciences Pokhara, Nepal.

出版信息

Indian J Dermatol. 2010 Jul-Sep;55(3):233-7. doi: 10.4103/0019-5154.70670.

Abstract

BACKGROUND

Cutaneous tuberculosis (TB) is essentially an invasion of the skin by Mycobacterium tuberculosis, the same bacteria that causes pulmonary tuberculosis.

AIM

This study was conducted to study the common types of cutaneous TB and to find the management pattern in a tertiary teaching hospital in Pokhara, Nepal.

MATERIALS AND METHODS

All the cases of cutaneous TB were biopsied and furthermore investigated by performing Mantoux test, sputum examination, fine needle aspiration cytology, chest X-ray and ELISA.

RESULTS

In this study, we found that tuberculosis verrucous cutis (48%) had a higher incidence than other types of cutaneous TB. More males were affected than were females (1.2:1). Commonly affected sites were the limb and the buttock (48%). The most commonly affected age group was 16-25 years (40%). All cases (except two) were more than 15 mm in size in the Mantoux test. The histopathological picture was typical in all except three cases. All patients were treated with antitubercular treatment as per the national guidelines.

CONCLUSION

The most common type of cutaneous TB was tuberculosis verrucous cutis and the most commonly affected sites were the limb and the buttock. As cutaneous TB sometimes reflects the presence of pulmonary tuberculosis, its incidence should not be ignored.

摘要

背景

皮肤结核本质上是由结核分枝杆菌侵袭皮肤所致,该细菌也是引发肺结核的病菌。

目的

本研究旨在探究尼泊尔博卡拉一家三级教学医院中皮肤结核的常见类型,并找出其治疗模式。

材料与方法

对所有皮肤结核病例进行活检,并进一步通过结核菌素试验、痰液检查、细针穿刺细胞学检查、胸部X线检查及酶联免疫吸附测定(ELISA)进行调查。

结果

在本研究中,我们发现疣状皮肤结核(48%)的发病率高于其他类型的皮肤结核。男性受累多于女性(比例为1.2:1)。常见受累部位为四肢和臀部(48%)。最常受累的年龄组为16 - 25岁(40%)。除两例外,所有病例的结核菌素试验硬结直径均超过15毫米。除三例病例外,所有病例的组织病理学表现均典型。所有患者均按照国家指南接受抗结核治疗。

结论

皮肤结核最常见的类型为疣状皮肤结核,最常受累部位为四肢和臀部。由于皮肤结核有时反映出肺结核的存在,其发病率不应被忽视。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0130/2965907/d4ab8640ca36/IJD-55-233-g001.jpg

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