Kernoff P B
Royal Free Hospital, London, England.
Prog Clin Biol Res. 1990;324:47-56.
Extensive worldwide experience with PE-fractionated porcine factor VIII concentrate has confirmed the expectation that the produce has an important place in the management of hemophiliacs with inhibitors, and that the problems which constrained the use of the original animal factor VIII concentrates have been largely overcome. A particular advantage, compared with PCCs and derivatives, is that dosage and effects can be monitored with conventional coagulation tests.
全球范围内对猪源因子VIII浓缩物（PE-分馏）的广泛经验证实了人们的预期，即该产品在有抑制剂的血友病患者管理中占有重要地位，并且在很大程度上克服了限制原始动物源性因子VIII浓缩物使用的问题。与凝血酶原复合物（PCCs）及其衍生物相比，一个特别的优势是可以通过传统凝血试验监测剂量和效果。
