Jordan Bryan D, Wright Elizabeth Laura
University of Alabama at Birmingham Hospital, Birmingham, Alabama, USA.
AANA J. 2010 Oct;78(5):387-92.
Discovered in 1898 by British chemists, xenon is a rare gas belonging to the noble gases of the periodic table. Xenon is used in many different ways, from high-intensity lamps to jet propellant, and in 1939, its anesthetic properties were discovered. Xenon exerts its anesthetic properties, in part, through the noncompetitive inhibition of N-methyl-D-aspartate receptors. Currently, xenon is being used primarily throughout Europe; however, the high price of manufacturing and scavenging the noble gas has discouraged more widespread use. As technology in anesthetic delivery improves, xenon is being investigated further as a possible replacement for nitrous oxide as an inhalational agent. This article reviews the anesthetic properties of xenon and current and potential research about the gas.
氙气于1898年被英国化学家发现,是一种属于元素周期表中稀有气体的稀有气体。氙气有多种不同用途,从高强度灯到喷气推进剂,1939年,其麻醉特性被发现。氙气部分通过对N-甲基-D-天冬氨酸受体的非竞争性抑制发挥其麻醉特性。目前,氙气主要在欧洲各地使用;然而,制造和清除这种稀有气体的高昂成本阻碍了其更广泛的应用。随着麻醉输送技术的改进,氙气作为一氧化二氮吸入剂的一种可能替代品正被进一步研究。本文综述了氙气的麻醉特性以及关于这种气体的当前和潜在研究。