Scarpino O, Pelliccioni G, Guidi M, Mauro A M, Mercante O
Instituto delle Malattie del Sistema Nervoso, Università di Ancona, Italia.
Rev Neurol (Paris). 1990;146(1):36-40.
A 58 year-old man with a 4-year history of Parkinson's disease developed a myoclonic syndrome with photosensitivity. The photo-convulsive response progressively worsened when therapy with levodopa, carbidopa and biperiden was interrupted. A marked reduction of the photosensitivity was obtained with bromocriptine. This case suggests that both diseases are correlated with a multiple degenerative process of the dopaminergic inhibitory pathways.
一名患有4年帕金森病病史的58岁男性出现了伴有光敏性的肌阵挛综合征。当左旋多巴、卡比多巴和安坦的治疗中断时,光惊厥反应逐渐恶化。使用溴隐亭后光敏性明显降低。该病例表明这两种疾病都与多巴胺能抑制通路的多重退行性过程相关。