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[帕金森病与癫痫:生物不相容性假说]

[Parkinson's disease and epilepsy: hypothesis of biological incompatibility].

作者信息

De Angelis G, Vizioli R

出版信息

Rev Neurol (Paris). 1984;140(6-7):440-2.

PMID:6431587
Abstract

The case of a 74-year-old woman, affected since the age of 20 by generalized convulsive fits and who began to show at the age of 63 signs of Parkinson's disease is reported. The epileptic features showed no change while Parkinson's disease got worse. Further, every convulsive fit was followed by a transitory improvement of the extrapyramidal disorders. After a review of the literature on the rare association of Parkinson's disease with epilepsy, the hypothesis of a biological incompatibility between the two diseases is considered.

摘要

报告了一名74岁女性的病例,她自20岁起就患有全身性惊厥发作,63岁时开始出现帕金森病症状。癫痫特征没有变化,而帕金森病病情加重。此外,每次惊厥发作后锥体外系障碍都会有短暂改善。在回顾了关于帕金森病与癫痫罕见关联的文献后,考虑了这两种疾病之间存在生物学不相容性的假说。

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