Department of Gynecology, Lis Maternity Hospital, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
Fertil Steril. 2011 Mar 1;95(3):1159-60. doi: 10.1016/j.fertnstert.2010.10.014. Epub 2010 Nov 10.
Many cases of ectopic pregnancy will spontaneously resolve, so that "watchful waiting" and β-hCG follow-up will separate true viable ectopic pregnancies from spontaneously resolving ectopic pregnancies. Withholding methotrexate in patients with spontaneously resolving ectopic pregnancies and administering it in only true viable ectopic pregnancies will no doubt decrease published success rates for this therapy.
许多异位妊娠病例会自行消退,因此“密切观察等待”和β-hCG 随访将区分真正有活力的异位妊娠和自行消退的异位妊娠。在自行消退的异位妊娠患者中不使用甲氨蝶呤,而仅在真正有活力的异位妊娠中使用,无疑会降低该疗法的发表成功率。