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髋部骨折术后的电解质紊乱和不同认知及功能患者群体中的钠离子变化。

Hip fracture post-operation dysnatremia and Na+-courses in different cognitive and functional patient groups.

机构信息

Department of Geriatrics, Rabin Medical Center, Beilinson Hospital, Sackler School of Medicine, Tel Aviv University, 39 Jabotinski St, Petah Tikva 49100, Israel.

出版信息

Arch Gerontol Geriatr. 2011 Sep-Oct;53(2):179-82. doi: 10.1016/j.archger.2010.10.014. Epub 2010 Nov 9.

Abstract

The aim of the study was to investigate Na(+)-course of hip fracture patients in relation to demographic and clinical parameters. Data on 155 older hip fracture patients were analyzed retrospectively. Clinical parameters and serum Na(+) on admission (Na1), during 24h pre-op. (Na2), during 24h post-op. (Na3), and pre-discharge (Na4) were recorded. Hyponatremia and hypernatremia rates pre- and post-operation were 26.5%, 2.6%, 24.5% and 5.8%. Higher Na3 (138.76 ± 4.4 mEq/l) vs. Na1 (137.69 ± 4.5 mEq/l) (p = 0.004) and correlation between age and Na3 (p = 0.021) was found. Mean serum Na(+) of impaired mental status (IMS) vs. normal patients and of partially/independent vs. dependent patients were higher (p < 0.05). More complications occurred in IMS patients tending to higher Na3 in patients with complications. No differences in Na(+)-courses were found according to sex or co-morbidities. Dysnatremia is highly prevalent in older hip fracture patients. A distinct post-operative increase in serum Na(+) was found, higher in the cognitively and functionally impaired patients. It seems that the Na(+) increase characterizes more IMS patients who suffer more complications, but does not necessarily indicate complications. We recommend surveillance of serum Na(+), particularly in cognitively and functionally impaired older patients in whom the risk of hypernatremia and complications is higher.

摘要

本研究旨在探讨髋部骨折患者的钠(Na+)变化与人口统计学和临床参数的关系。回顾性分析了 155 例老年髋部骨折患者的数据。记录了临床参数和入院时(Na1)、术前 24 小时内(Na2)、术后 24 小时内(Na3)和出院前(Na4)的血清 Na+。术前和术后低钠血症和高钠血症的发生率分别为 26.5%、2.6%、24.5%和 5.8%。发现术后 Na3(138.76±4.4 mEq/l)高于 Na1(137.69±4.5 mEq/l)(p=0.004),年龄与 Na3 之间存在相关性(p=0.021)。有认知障碍的患者(IMS)与正常患者相比,血清 Na+的平均值更高(p<0.05),部分/独立患者与依赖患者相比,血清 Na+的平均值更高(p<0.05)。IMS 患者并发症更多,Na3 值更高。性别或合并症与 Na+变化无差异。认知和功能障碍的患者 Na3 值更高。

老年髋部骨折患者中存在高发生率的低钠血症和高钠血症。术后血清 Na+明显升高,认知和功能障碍患者的 Na+升高更为明显。似乎 Na+升高的患者更容易发生 IMS,并发更多并发症,但这并不一定表明并发症的发生。我们建议监测血清 Na+,特别是在认知和功能障碍的老年患者中,这些患者发生高钠血症和并发症的风险更高。

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