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老年人认知障碍与过早死亡之间的关系。

Relation between cognitive impairment and early death in the elderly.

作者信息

Eagles J M, Beattie J A, Restall D B, Rawlinson F, Hagen S, Ashcroft G W

机构信息

Ross Clinic, Royal Cornhill Hospital, Aberdeen.

出版信息

BMJ. 1990 Jan 27;300(6719):239-40. doi: 10.1136/bmj.300.6719.239.

Abstract

STUDY OBJECTIVE

To study the association between cognitive impairment and early death in elderly patients living in the community.

DESIGN

Case-control study of 410 patients assessed by the mental status questionnaire and followed up after three years.

SETTING

A general practice in Inverurie, Aberdeenshire, with 14,000 patients.

PATIENTS

205 Patients aged greater than or equal to 65 with cognitive impairment according to the mental status questionnaire (score less than or equal to 8) and 205 patients scoring greater than 8 on the questionnaire matched for age and sex.

MAIN OUTCOME MEASURE

Death.

RESULTS

The relative risk of death in the cognitively impaired patients overall was 3.5. Those patients who scored less than or equal to 7 on the mental status questionnaire were five times more likely to die than their controls. There was no difference in risk of death between those with severe or moderate cognitive impairment.

CONCLUSIONS

Cognitive impairment is associated with early death.

摘要

研究目的

研究社区老年患者认知障碍与过早死亡之间的关联。

设计

采用病例对照研究,对410名患者进行精神状态问卷调查,并随访三年。

研究地点

阿伯丁郡因弗鲁里的一家全科诊所,该诊所有14000名患者。

患者

根据精神状态问卷,205名年龄大于或等于65岁且有认知障碍的患者(得分小于或等于8分),以及205名在问卷上得分大于8分且年龄和性别匹配的患者。

主要观察指标

死亡。

结果

总体而言,认知障碍患者的死亡相对风险为3.5。在精神状态问卷上得分小于或等于7分的患者死亡可能性是对照组的五倍。重度或中度认知障碍患者的死亡风险没有差异。

结论

认知障碍与过早死亡有关。

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Cognitive impairment and early death in the elderly.老年人的认知障碍与过早死亡
BMJ. 1990 Mar 10;300(6725):681-2. doi: 10.1136/bmj.300.6725.681-b.

本文引用的文献

1
The outcome of mental breakdown in old age.老年人精神崩溃的后果。
Br Med J. 1951 Mar 3;1(4704):436-40. doi: 10.1136/bmj.1.4704.436.
3
THE PROGNOSIS IN "ORGANIC BRAIN" SYNDROMES.“器质性脑”综合征的预后
Am J Psychiatry. 1964 Mar;120:878-81. doi: 10.1176/ajp.120.9.878.
5
The natural history of mental disorder in old age.老年精神障碍的自然史。
J Ment Sci. 1955 Apr;101(423):281-301. doi: 10.1192/bjp.101.423.281.
7
A new clinical scale for the staging of dementia.一种用于痴呆分期的新临床量表。
Br J Psychiatry. 1982 Jun;140:566-72. doi: 10.1192/bjp.140.6.566.

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