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老年内科住院患者的认知障碍:检测及相关的六个月结局

Cognitive impairment in elderly medical inpatients: detection and associated six-month outcomes.

作者信息

Joray Sabine, Wietlisbach Vincent, Büla Christophe J

机构信息

Division of Geriatric Medicine, Department of Internal Medicine, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland.

出版信息

Am J Geriatr Psychiatry. 2004 Nov-Dec;12(6):639-47. doi: 10.1176/appi.ajgp.12.6.639.

Abstract

OBJECTIVE

The authors examined the relationship of cognitive impairment at hospital admission to 6-month outcome (hospital readmission, nursing home admission, and death) in a cohort of elderly medical inpatients.

METHODS

A group of 401 medical inpatients age 75 and older underwent a comprehensive geriatric assessment at hospital admission and were followed up for 6 months. Cognitive impairment was defined as a score <24 on the Mini-Mental State Exam. Detection was assessed through blinded review of discharge summary. Follow-up data were gathered from the centralized billing system (hospital and nursing home admissions) and from proxies (death).

RESULTS

Cognitive impairment was present in 129 patients (32.3%). Only 48 (37.2%) were detected; these had more severe impairment than undetected cases. During follow-up, cognitive impairment, whether detected or not, was associated with death and nursing home admission. After adjustment for health, functional, and socioeconomic status, an independent association remained only for nursing home admission in subjects with detected impairment. Those with undetected impairment appeared to be at intermediate risk, but this relationship was not statistically significant.

CONCLUSION

In these elderly medical inpatients, cognitive impairment was frequent, rarely detected, and associated with nursing home admission during follow-up. Although this association was stronger in those with detected impairment, these results support the view that acute hospitalization presents an opportunity to better detect cognitive impairment in elderly patients and target further interventions to prevent adverse outcomes such as nursing home admission.

摘要

目的

作者研究了老年内科住院患者入院时的认知障碍与6个月结局(再次入院、入住养老院和死亡)之间的关系。

方法

一组401名75岁及以上的内科住院患者在入院时接受了全面的老年医学评估,并进行了6个月的随访。认知障碍定义为简易精神状态检查得分<24分。通过对出院小结的盲法审查来评估认知障碍的检出情况。随访数据从集中计费系统(医院和养老院入院情况)以及代理人(死亡情况)处收集。

结果

129名患者(32.3%)存在认知障碍。仅48例(37.2%)被检出;这些患者的认知障碍比未被检出的患者更为严重。在随访期间,认知障碍无论是否被检出,均与死亡和入住养老院有关。在对健康、功能和社会经济状况进行调整后,仅在被检出存在认知障碍的患者中,入住养老院存在独立相关性。未被检出存在认知障碍的患者似乎处于中等风险,但这种关系无统计学意义。

结论

在这些老年内科住院患者中,认知障碍很常见,很少被检出,且与随访期间入住养老院有关。尽管这种相关性在被检出存在认知障碍的患者中更强,但这些结果支持这样一种观点,即急性住院为更好地检出老年患者的认知障碍以及针对预防入住养老院等不良结局进行进一步干预提供了一个契机。

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