Jagiellonian University Medical College, Faculty of Medicine, 12 Św. Anny Street, 31-008 Kraków, Poland.
Arch Gerontol Geriatr. 2012 Jul-Aug;55(1):22-4. doi: 10.1016/j.archger.2011.06.034. Epub 2011 Jul 20.
Frailty syndrome (FS) and cognitive impairment are associated with an increased risk of falls, disability, hospitalization and death. We investigated prognostic meaning of FS and cognitive impairment in persons ≥ 65 years, living in 2 nursing homes. Information about the health status of patients was gathered from history, medical documentation, test assessing FS, according to the Canadian Study of Health and Aging-Clinical Frailty Scale (CSHA-CFS) and the Mini-Mental State Examination (MMSE). The study group included 66 women and 20 men, between 66 and 101 years of age (mean ± S.D.=83.8 ± 8.3 years). The frequency of severe frailty (CSHA-CFS=7) among the elderly living in nursing homes was 34.9%, while severe cognitive impairment (MMSE<18) was present in 55.8%. Residents with severe FS and MMSE<18 consisted 33.7% of examined and 50.0% of those who died during 12-month follow-up, p<0.05. Individuals with severe FS and severe cognitive impairment (n=29) as compared to all other patients, were significantly less probable (59% vs. 79%, p=0.03) to survive one year. Neither frailty, nor dementia, nor severe FS or cognitive impairment when considered separately was associated with higher mortality rate. The risk assessment in severely disabled geriatric patients is best performed with measures of functional and cognitive function considered jointly, but not separately.
衰弱综合征 (FS) 和认知障碍与跌倒、残疾、住院和死亡风险增加相关。我们研究了 2 家养老院中≥65 岁人群 FS 和认知障碍的预后意义。患者的健康状况信息来自病史、医疗记录和评估 FS 的测试,根据加拿大老龄化健康研究-临床衰弱量表 (CSHA-CFS) 和简易精神状态检查 (MMSE) 进行评估。研究组包括 66 名女性和 20 名男性,年龄在 66 至 101 岁之间(平均 ± 标准差=83.8 ± 8.3 岁)。养老院中衰弱严重程度较高(CSHA-CFS=7)的老年人比例为 34.9%,而认知严重障碍(MMSE<18)的比例为 55.8%。在 12 个月的随访期间,严重 FS 和 MMSE<18 的居民占检查人群的 33.7%,占死亡人群的 50.0%,p<0.05。与所有其他患者相比,严重 FS 和严重认知障碍的个体(n=29)更不可能存活 1 年(59% vs. 79%,p=0.03)。单独考虑衰弱、痴呆、严重 FS 或认知障碍与更高的死亡率无关。严重残疾老年患者的风险评估最好通过联合考虑功能和认知功能的措施进行,而不是单独考虑。