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会议报告:2010年秀丽隐杆线虫神经生物学会议,美国威斯康星大学

Meeting report: 2010 Caenorhabditis elegans Neurobiology Meeting, University of Wisconsin, USA.

作者信息

Mulcahy Ben, Ient Ben

机构信息

School of Biological Sciences, University of Southampton, Building 85, Highfield Campus, Southampton SO17 1BJ, UK.

出版信息

Invert Neurosci. 2010 Dec;10(2):53-61. doi: 10.1007/s10158-010-0110-1. Epub 2010 Nov 11.

DOI:10.1007/s10158-010-0110-1
PMID:21069413
Abstract

Against the backdrop of the scenic Lake Mendota, the C. elegans Neurobiology Meeting came to a head. Expertly organised by Brian Ackley and Bruce Bamber and hosted at the accommodating University of Wisconsin, the meeting brought together recent contributions from many of the major research groups working on the neurobiology of C. elegans. With seven keynote speakers, 57 verbal presentations and hundreds of posters, this exciting event spanned a fascinating 3 days from 27 June to 30 June 2010. In keeping with the tradition of this conference, the event on the whole was spearheaded by young investigators from several research institutions. The meeting served to emphasise the gains enjoyed by taking advantage of the genetic tractability of the worm. A thread that ran through the meeting was the importance of integrating data across different levels of biological organisation to permit delineation of the physiology underpinning discrete behavioural states. Recent advances in optogenetics and microfluidics were at the forefront of refining these analyses. The presentations discussed in this meeting report are a selection which reflects this overarching theme.

摘要

在风景秀丽的门多塔湖的映衬下,秀丽隐杆线虫神经生物学会议达到了高潮。该会议由布莱恩·阿克利和布鲁斯·班伯精心组织,并在热情好客的威斯康星大学举办,汇聚了许多致力于秀丽隐杆线虫神经生物学研究的主要研究小组的最新成果。会议于2010年6月27日至30日举行,为期精彩的3天,有7位主旨演讲者、57场口头报告以及数百份海报展示。秉承本次会议的传统,整个活动由来自多个研究机构的年轻研究人员牵头。此次会议强调了利用线虫的遗传易处理性所取得的成果。贯穿会议的一个主题是整合不同生物组织层次的数据以描绘支撑离散行为状态的生理学的重要性。光遗传学和微流体技术的最新进展处于完善这些分析的前沿。本会议报告中讨论的报告是反映这一总体主题的精选内容。

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High-throughput study of synaptic transmission at the neuromuscular junction enabled by optogenetics and microfluidics.基于光遗传学和微流控技术的神经肌肉接头突触传递的高通量研究。
J Neurosci Methods. 2010 Aug 15;191(1):90-3. doi: 10.1016/j.jneumeth.2010.05.019. Epub 2010 Jun 9.
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The monoaminergic modulation of sensory-mediated aversive responses in Caenorhabditis elegans requires glutamatergic/peptidergic cotransmission.单胺能调制秀丽隐杆线虫感觉介导的厌恶反应需要谷氨酸能/肽能共传递。
J Neurosci. 2010 Jun 9;30(23):7889-99. doi: 10.1523/JNEUROSCI.0497-10.2010.
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A differential role for neuropeptides in acute and chronic adaptive responses to alcohol: behavioural and genetic analysis in Caenorhabditis elegans.
神经肽在急性和慢性酒精适应反应中的差异作用:秀丽隐杆线虫的行为和遗传分析。
PLoS One. 2010 May 3;5(5):e10422. doi: 10.1371/journal.pone.0010422.
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Neuropeptide feedback modifies odor-evoked dynamics in Caenorhabditis elegans olfactory neurons.神经肽反馈调节秀丽隐杆线虫嗅觉神经元中海马体诱发的动力学。
Nat Neurosci. 2010 May;13(5):615-21. doi: 10.1038/nn.2526. Epub 2010 Apr 4.
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A secreted complement-control-related protein ensures acetylcholine receptor clustering.一种分泌型补体控制相关蛋白可确保乙酰胆碱受体聚集。
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The quest for action potentials in C. elegans neurons hits a plateau.对线虫神经元动作电位的探索陷入了停滞。
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