Department of Obstetrics and Gynecology, Tohoku University Graduate School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai 980-8574, Japan.
Int J Clin Oncol. 2010 Dec;15(6):531-42. doi: 10.1007/s10147-010-0138-6. Epub 2010 Nov 11.
Endometrial carcinoma is one of the most common gynecologic malignancies in Japan and its incidence has increased recently. Although surgery is the cornerstone of the management of patients with endometrial cancer, there is significant variation in Japan with regard to the type of hysterectomy employed. Additionally, it remains controversial whether full nodal staging is required in all patients. Furthermore, adjuvant therapy differs between Japan and Western countries. To delineate clearly the standard of care for endometrial cancer treatment in Japan, the guidelines for the treatment of endometrial cancer were published in 2006 and revised in 2009. The 2009 edition included topics not addressed in the previous edition including the treatment of mesenchymal tumors, for example leiomyosarcoma, and sections covering the treatment of serous and clear-cell adenocarcinoma. These guidelines are composed of nine chapters and include nine algorithms. The guidelines also contain fifty-one clinical questions (CQs) and each CQ consists of recommendations, background, explanations, and references. The treatment recommendations herein are tailored to reflect current Japanese clinical practice and ensure equitable care for all Japanese women diagnosed with endometrial cancer.
子宫内膜癌是日本最常见的妇科恶性肿瘤之一，其发病率最近有所增加。尽管手术是子宫内膜癌患者治疗的基石，但日本在使用的子宫切除术类型方面存在显著差异。此外，是否所有患者都需要进行全面的淋巴结分期仍然存在争议。此外，日本和西方国家的辅助治疗也存在差异。为了明确日本子宫内膜癌治疗的标准，2006 年发布了子宫内膜癌治疗指南，并于 2009 年进行了修订。2009 年版包括了前一版未涉及的主题，例如间叶性肿瘤（例如平滑肌肉瘤），以及涵盖浆液性和透明细胞腺癌治疗的章节。这些指南由九个章节组成，包括九个算法。指南还包含五十一个临床问题（CQ），每个 CQ 都包含建议、背景、解释和参考文献。此处的治疗建议旨在反映当前日本的临床实践，并确保所有被诊断患有子宫内膜癌的日本女性都能得到公平的治疗。
