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结节性多动脉炎伴大量腹膜后出血的一种罕见并发症:病例报告

An unusual complication of polyarteritis nodosa with massive retroperitoneal hemorrhage: a case report.

作者信息

Peddi Prashanth, Kalavakunta Jagadeesh K, Annakula Madhavi, Armstrong John R

机构信息

Department of Internal Medicine, Michigan State University, Lansing, MI, USA.

出版信息

Int Arch Med. 2010 Nov 11;3:31. doi: 10.1186/1755-7682-3-31.

Abstract

UNLABELLED

BACKGROUND AND CASE REPORT: Polyarteritis Nodosa (PAN) is a systemic necrotizing vasculitis that affects medium-sized and occasionally involves small arteries leading to the disruption of the internal and external elastic lamina and contribute to the development of aneurysms. Aneurysms develop at bifurcation of major blood vessels; they are prone to thrombosis, rupture and haemorrhage. Retroperitoneal haemorrhage around kidneys was previously reported in patients with PAN. We report a case of massive retroperitoneal bleeding from inferior pancreaticoduodenal artery aneurysm rupture in a 70-year-old female with PAN.

CONCLUSION

Prognosis of untreated PAN is very poor with 20% 5 year survival rate, therefore early recognition of the disease will prevent catastrophic complications and improves survival.

摘要

未标注

背景与病例报告:结节性多动脉炎(PAN)是一种系统性坏死性血管炎,累及中等大小动脉,偶尔也会累及小动脉,导致内、外弹性膜破坏,并促使动脉瘤形成。动脉瘤多发生于主要血管的分叉处,易发生血栓形成、破裂和出血。此前曾有PAN患者发生肾周腹膜后出血的报道。我们报告一例70岁患有PAN的女性因胰十二指肠下动脉瘤破裂导致大量腹膜后出血的病例。

结论

未经治疗的PAN预后很差,5年生存率仅为20%,因此早期识别该疾病可预防灾难性并发症并提高生存率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b44/2993688/b4c52955185d/1755-7682-3-31-1.jpg

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