Graduate Institute of Healthcare Administration, Kaohsiung Medical University, 100, Shih-Chun 1st Road, Kaohsiung, Taiwan.
BMC Musculoskelet Disord. 2010 Nov 12;11:261. doi: 10.1186/1471-2474-11-261.
The health-related quality of life (HRQoL) is currently weighted more heavily when evaluating health status, particularly regarding medical treatments and interventions. However, it is rarely used by physicians to compare responsiveness. Additionally, responsiveness estimates derived by the Harris Hip Score (HHS) and the Short Form 36 (SF-36) before and after revision total hip arthroplasty (THA) have not been clinically compared. This study compared responsiveness and minimal important differences (MID) between HHS and SF-36.
All revision THA patients completed the disease-specific HHS and the generic SF-36 before and 6 months after surgery. Scores using these instruments were interpreted by generalized estimating equation (GEE) before and after revision THA. The bootstrap estimation and modified Jacknife test were used to derive 95% confidence intervals for differences in the responsiveness estimates.
Comparisons of effect size (ES), standardized response means (SRM), relative efficiency (RE) (>1) and MID indicated that the responsiveness of HHS was superior to that of SF-36. The ES and SRM for pain and physical functions in the HHS were significantly larger than those of the SF-36 (p < 0.001).
The data in this study indicated that clinicians and health researchers should weight disease-specific measures more heavily than generic measures when evaluating treatment outcomes.
目前,在评估健康状况时,健康相关生活质量(HRQoL)的权重越来越大,特别是在涉及医疗治疗和干预措施时。然而,医生很少用它来比较反应度。此外,Harris 髋关节评分(HHS)和简化 36 项健康调查(SF-36)在全髋关节翻修前后的反应度估计值尚未进行临床比较。本研究比较了 HHS 和 SF-36 的反应度和最小有意义差异(MID)。
所有接受全髋关节翻修的患者在手术前后均完成了特定于疾病的 HHS 和通用的 SF-36。使用广义估计方程(GEE)在翻修前后解释这些工具的评分。使用自举估计和改进的 Jacknife 检验得出反应度估计值差异的 95%置信区间。
通过效应大小(ES)、标准化反应均值(SRM)、相对效率(RE)(>1)和 MID 的比较,表明 HHS 的反应度优于 SF-36。HHS 的疼痛和身体功能的 ES 和 SRM 明显大于 SF-36(p < 0.001)。
本研究的数据表明,临床医生和健康研究人员在评估治疗结果时,应更重视特定于疾病的衡量标准,而不是通用的衡量标准。