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杜兴氏肌营养不良症患者的血浆甲状腺素水平

Plasma thyroxine levels in Duchenne muscular dystrophy.

作者信息

John H A

机构信息

Department of Genetics, University of Edinburgh, Scotland.

出版信息

Experientia. 1990 Mar 15;46(3):301-3. doi: 10.1007/BF01951772.

DOI:10.1007/BF01951772
PMID:2107095
Abstract

Some young Duchenne muscular dystrophy (DMD) patients (3-7 years) had total thyroxine (T4) levels and T4 to thyroxine binding globulin (TBG) ratios above the normal range and significantly increased free thyroxine indices (fT4I) which, however, remained within the normal range. Older DMD patients (7-11 years) had T4 and TBG levels and fT4I similar to normal. In both DMD groups the thyroxine binding index (TBI) values were in the normal range.

摘要

一些年轻的杜兴氏肌营养不良症(DMD)患者(3至7岁)的总甲状腺素(T4)水平以及T4与甲状腺素结合球蛋白(TBG)的比率高于正常范围,游离甲状腺素指数(fT4I)显著升高,不过仍在正常范围内。年龄较大的DMD患者(7至11岁)的T4、TBG水平和fT4I与正常人相似。在两个DMD组中,甲状腺素结合指数(TBI)值均在正常范围内。

相似文献

1
Plasma thyroxine levels in Duchenne muscular dystrophy.杜兴氏肌营养不良症患者的血浆甲状腺素水平
Experientia. 1990 Mar 15;46(3):301-3. doi: 10.1007/BF01951772.
2
Measurement of thyroxine uptake from serum by cultured human hepatocytes as an index of thyroid status: reduced thyroxine uptake from serum of patients with nonthyroidal illness.通过培养的人肝细胞测量血清中甲状腺素摄取量作为甲状腺状态指标:非甲状腺疾病患者血清中甲状腺素摄取量降低。
J Clin Endocrinol Metab. 1985 Dec;61(6):1046-52. doi: 10.1210/jcem-61-6-1046.
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Reference intervals from birth to adulthood for serum thyroxine (T4), triiodothyronine (T3), free T3, free T4, thyroxine binding globulin (TBG) and thyrotropin (TSH).从出生到成年期血清甲状腺素(T4)、三碘甲状腺原氨酸(T3)、游离T3、游离T4、甲状腺素结合球蛋白(TBG)和促甲状腺激素(TSH)的参考区间。
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A reappraisal of the binding characteristics of human thyroxine-binding globulin for 3,5,3'-triiodothyronine and thyroxine.人甲状腺素结合球蛋白与3,5,3'-三碘甲状腺原氨酸和甲状腺素结合特性的重新评估。
J Clin Endocrinol Metab. 1985 Jan;60(1):42-7. doi: 10.1210/jcem-60-1-42.

本文引用的文献

1
Hypothyroid myopathy.甲状腺功能减退性肌病
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2
An inhibitor of the binding of thyroid hormones to serum proteins is present in extrathyroidal tissues.甲状腺外组织中存在一种甲状腺激素与血清蛋白结合的抑制剂。
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Transport of protein-bound hormones into tissues in vivo.体内蛋白质结合激素向组织的转运。
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The transport of thyroid hormones.
Clin Sci (Lond). 1983 Oct;65(4):337-42. doi: 10.1042/cs0650337.
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Euthyroid hyperthyroxinemia.
Ann Intern Med. 1983 Mar;98(3):366-78. doi: 10.7326/0003-4819-98-3-366.
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Dystrophin: the protein product of the Duchenne muscular dystrophy locus.肌营养不良蛋白:杜氏肌营养不良基因座的蛋白质产物。
Cell. 1987 Dec 24;51(6):919-28. doi: 10.1016/0092-8674(87)90579-4.
8
Immunoelectron microscopic localization of dystrophin in myofibres.肌营养不良蛋白在肌纤维中的免疫电子显微镜定位
Nature. 1988 Jun 30;333(6176):863-6. doi: 10.1038/333863a0.
9
Immunostaining of skeletal and cardiac muscle surface membrane with antibody against Duchenne muscular dystrophy peptide.用抗杜氏肌营养不良肽抗体对骨骼肌和心肌表面膜进行免疫染色。
Nature. 1988 Jun 30;333(6176):861-3. doi: 10.1038/333861a0.
10
Transcription of the dystrophin gene in human muscle and non-muscle tissue.肌营养不良蛋白基因在人体肌肉和非肌肉组织中的转录。
Nature. 1988 Jun 30;333(6176):858-60. doi: 10.1038/333858a0.