Gerencia de Leishmanioses, Funbdação de Medicina Tropical do Amazonas, Manaus, Brazil.
Parasitol Res. 2011 Mar;108(3):671-7. doi: 10.1007/s00436-010-2139-9. Epub 2010 Nov 12.
In the State of Amazonas, American tegumentary leishmaniasis is endemic and presents a wide spectrum of clinical variability due to the large diversity of circulating species in the region. Isolates from patients in Manaus and its metropolitan region were characterized using monoclonal antibodies and isoenzymes belonging to four species of the parasite: Leishmania (Viannia) guyanensis, 73% (153/209); Leishmania (Viannia) braziliensis, 14% (30/209); Leishmania (Leishmania) amazonensis, 8% (17/209); and Leishmania (Viannia) naiffii, 4% (9/209). The most prevalent species was L. (V.) guyanensis. The principal finding of this study was the important quantity of infections involving more than one parasite species, representing 14% (29/209) of the total. The findings obtained in this work regarding the parasite are further highlighted by the fact that these isolates were obtained from clinical samples collected from single lesions.
在亚马逊州，皮肤利什曼病流行，由于该地区循环种的多样性很大，临床表现变化很大。使用单克隆抗体和同工酶对来自马瑙斯及其大都市区的患者分离株进行了鉴定，这些分离株属于寄生虫的四个种：利什曼原虫（Viannia）圭亚那种，占 73%（153/209）；利什曼原虫（Viannia）巴西种，占 14%（30/209）；利什曼原虫（Leishmania）亚马逊种，占 8%（17/209）；和利什曼原虫（Viannia）naiffii，占 4%（9/209）。最流行的种是 L.（V.）圭亚那种。这项研究的主要发现是涉及多种寄生虫的感染数量很多，占总数的 14%（29/209）。这项工作中关于寄生虫的发现进一步突出了这样一个事实，即这些分离株是从单个病变采集的临床样本中获得的。
