Department of Analytical Chemistry, University of Barcelona, Martí i Franquès 1-11, E-08028 Barcelona, Spain.
Rapid Commun Mass Spectrom. 2010 Dec 15;24(23):3469-77. doi: 10.1002/rcm.4801.
The fragmentation of bisphenol A diglycidyl ether (BADGE), bisphenol F diglycidyl ether (BFDGE) and their derivatives was studied by electrospray ionization tandem mass spectrometry. Multiple-stage mass spectrometry and accurate mass measurements were combined to establish the fragmentation pathways. BADGEs and BFDGEs tend to form ammonium adducts under electrospray conditions which fragmented easily. The fragmentation of M+NH(4) for BADGEs started with the cleavage of the phenyl-alkyl bond, which was followed by the α-cleavage of the ether group to generate the characteristic product ions at m/z 135, C(9)H(11)O, and m/z 107, C(7)H(7)O. The fragmentation of the BFDGE isomer mixtures was studied by on-line reversed-phase liquid chromatography coupled to multiple-stage mass spectrometry (LC/MS(n)). Information obtained from product ion spectra for each BFDGE isomer and its comparison with the fragmentation pathway of BADGE allowed each isomer and the chromatographic elution order to be identified.
采用电喷雾串联质谱法研究了双酚 A 二缩水甘油醚（BADGE）、双酚 F 二缩水甘油醚（BFDGE）及其衍生物的断裂情况。多级质谱和精确质量测量相结合，建立了断裂途径。在电喷雾条件下，BADGEs 和 BFDGEs 容易形成铵加合物，这些加合物容易断裂。[M+NH4]+ 形式的 BADGEs 断裂首先是苯基-烷基键的断裂，然后是醚基的α断裂，生成特征产物离子 m/z 135，[C9H11O]+，和 m/z 107，[C7H7O]+。通过在线反相液相色谱-多级质谱（LC/MS(n)）研究了 BFDGE 异构体混合物的断裂情况。从每个 BFDGE 异构体的产物离子光谱中获得的信息及其与 BADGE 断裂途径的比较，允许鉴定每个异构体及其色谱洗脱顺序。
