Research Institute of Innovative Technology for the Earth, 9-2, Kizugawadai, Kizugawa, Kyoto 619-0292, Japan.
Future Microbiol. 2010 Oct;5(10):1475-81. doi: 10.2217/fmb.10.114.
Corynebacterium glutamicum is a nonpathogenic, GC-rich, Gram-positive bacterium with a long history in the industrial production of amino acids. Recently, the species has become of increasing interest as a model bacterium for closely related, medically important pathogenic species such as Corynebacterium diphtheriae and Mycobacterium tuberculosis. In this article, recent advances in understanding of the C. glutamicum regulatory network of genes involved in carbohydrate metabolism are reviewed with regards to sugar uptake, glycolysis and lactate production.
谷氨酸棒杆菌是一种非致病性、GC 含量高、革兰氏阳性细菌，在氨基酸的工业生产中有着悠久的历史。最近，该物种作为密切相关的、具有医学重要性的致病性物种（如白喉棒状杆菌和结核分枝杆菌）的模式细菌引起了越来越多的关注。本文综述了近年来对参与碳水化合物代谢的谷氨酸棒杆菌基因调控网络的理解的最新进展，涉及糖摄取、糖酵解和乳酸生成。
