Tidir A A, Levaniuk V F, Kuruts V M
Arkh Patol. 1978;40(7):57-61.
In the autopsy materials of 1972-1976, cytomegaly was diagnosed in 47 infants dying in the first year of life; two of them were found to have cytomegalovirusinvolvement of the thymus. The clinical course of the disease depended on the intensity of pathological lesions in organs and tissues associated with secondary infection. In the thymus, alongside with marked accidental involution, cytomegaloviral metamorphosis of the reticular epithelium and epithelium of Hassal bodies was found. Foci of calcinosis were observed in the parenchyma of the thymus. During the disease hypogammaglobulinemia was observed. A possible role of cytomegalovirus infection in the development of acquired immunodeficiency conditions in infants under one is suggested.
在1972年至1976年的尸检材料中，47名一岁内死亡的婴儿被诊断为细胞肿大；其中两例发现有巨细胞病毒累及胸腺。该病的临床病程取决于与继发感染相关的器官和组织中病理病变的强度。在胸腺中，除了明显的偶然萎缩外，还发现了网状上皮和哈氏小体上皮的巨细胞病毒变形。在胸腺实质中观察到钙化灶。患病期间观察到低丙种球蛋白血症。提示巨细胞病毒感染在一岁以下婴儿获得性免疫缺陷病发展过程中可能起作用。
