Tsinzerling V A, Vasil'eva G G, Indikova M G, Popov S D
Arkh Patol. 1990;52(7):16-20.
The results of examination of 87 children who died from a generalized cytomegalovirus infection in Elista (66 cases) in 1984-1985, 1988-89, and in Leningrad (21 cases) in 1988-89 are available. In the Elista material a considerable increase (from 21 to 66%) of severe forms of accidental transformation of thymus is observed in the second period comparing to the first one. The causes of a serious worsening of the immunological background remain unclear. Cytomegaly represented 3.85% of all dead children in the pathology department of the First Children Hospital of Leningrad. There was sialadenitis in 4 cases and generalized infection with involvement of the lungs, liver, kidneys, brain, myocardium, pancreas, adrenals in 17 cases. Cytomegaly was diagnosed in 3 of 5 cases of primary immunodeficiency. Diagnosis in some cases was confirmed by the DNA cytomegalovirus detection by means of PCR reaction.
现已有1984 - 1985年、1988 - 1989年在埃利斯塔（66例）以及1988 - 1989年在列宁格勒（21例）死于全身性巨细胞病毒感染的87名儿童的检查结果。在埃利斯塔的资料中，观察到与第一阶段相比，第二阶段胸腺意外转化的严重形式有显著增加（从21%增至66%）。免疫背景严重恶化的原因仍不清楚。在列宁格勒第一儿童医院病理科，巨细胞感染占所有死亡儿童的3.85%。4例有涎腺炎，17例有累及肺、肝、肾、脑、心肌、胰腺、肾上腺的全身性感染。5例原发性免疫缺陷病例中有3例诊断为巨细胞感染。部分病例通过聚合酶链反应检测巨细胞病毒DNA得以确诊。
