Pyrhönen S, Neuvonen E
Arch Virol. 1978;57(4):297-305. doi: 10.1007/BF01320069.
Using the immunodiffusion method, antibodies against human wart-virus were detected in dog, pig and cattle sera but not in horse and reindeer sera. Antibodies were found in 25 percent (28/114) of the dog sera, the prevalence of antibodies being fairly similar to that in children of the same age. By electron microscopy the antibodies in dog sera were shown to attach to and precipitate the human wart-virus particles, and in immunodiffusion the precipitation lines of human and dog sera were shown to be identical. Of the cattle sera studied, 10 percent (10/97) and of the pig sera 13 percent (5/40) gave a faint precipitation line, having identity with that given by the human sera, against human wart-virus. Conversely 18 percent (9/50) of adult human sera contained precipitating antibodies against a bovine papilloma antigen, probably bovine papilloma virus.
采用免疫扩散法，在犬、猪和牛的血清中检测到了抗人乳头瘤病毒的抗体，但在马和驯鹿的血清中未检测到。在25%（28/114）的犬血清中发现了抗体，其抗体流行率与同龄儿童相当。通过电子显微镜观察发现，犬血清中的抗体能够附着并沉淀人乳头瘤病毒颗粒，在免疫扩散试验中，人血清和犬血清的沉淀线显示为相同。在所研究的牛血清中，10%（10/97）以及猪血清中13%（5/40）针对人乳头瘤病毒产生了与人类血清相同的微弱沉淀线。相反，18%（9/50）的成人血清中含有针对牛乳头瘤抗原（可能是牛乳头瘤病毒）的沉淀抗体。
