Department of Oral Surgery and Radiology, School of Dentistry, Medical University of Graz, Austria.
Int J Oral Maxillofac Surg. 2011 Feb;40(2):195-9. doi: 10.1016/j.ijom.2010.10.008. Epub 2010 Nov 11.
Although computer assisted volumetric quantification of human maxillary sinuses is commonly used to measure volumetric changes during life, reliability data for this procedure are lacking. The objective of this retrospective study is to test a semi-automatic virtual volumetric analysis technique on 36 CT scans of human maxillary sinuses. Three examiners with different clinical experience performed all measurements in three replicates. As principle of proof, the technique was examined on 12 phantoms with known volumes. The validation of the method revealed that the mean relative error was 0.364%. For the retrospective volumetric measurements from maxillary sinuses the intra- and inter-examiner agreement was quantified using appropriate intraclass correlation coefficients (ICC 1,k and ICC 2,k) and the Bland-Altman analysis. ICC values ranging from 0.997 to 0.999 indicate almost perfect agreement for intra- and inter-examiner data. The Bland-Altman analysis demonstrated good intra- as well as inter-examiner agreement for the two proficient examiners and a lack of agreement for the untrained examiner. It can be concluded that this measurement procedure using CT scans could be strongly recommended for clinical application to determine the volume of human maxillary sinuses reliably.
尽管计算机辅助的人类上颌窦容积量化常用于测量生命过程中的容积变化，但该程序的可靠性数据尚缺乏。本回顾性研究的目的是测试一种半自动的虚拟容积分析技术在 36 例人类上颌窦 CT 扫描上的应用。3 名具有不同临床经验的检查者进行了所有 3 次重复测量。作为证明原则，该技术在 12 个具有已知体积的体模上进行了检验。方法验证表明，平均相对误差为 0.364%。对于上颌窦的回顾性容积测量，使用适当的组内相关系数（ICC1，k 和 ICC2，k）和 Bland-Altman 分析来量化内部和内部检查者之间的一致性。ICC 值范围从 0.997 到 0.999 表明内部和内部检查者数据之间几乎存在完美的一致性。 Bland-Altman 分析表明，对于两位熟练的检查者，内部和内部检查者之间的一致性良好，而对于未经训练的检查者则缺乏一致性。可以得出结论，使用 CT 扫描的这种测量程序可以强烈推荐用于临床应用，以可靠地确定人类上颌窦的体积。
